机构

• 上海药物研究所 [10]
• 合肥物质科学研究院 [6]
• 青岛生物能源与过程研... [4]
• 地质与地球物理研究所 [2]
• 金属研究所 [1]
• 长春光学精密机械与物... [1]
• 更多

采集方式

• OAI收割 [26]

内容类型

• 期刊论文 [26]

发表日期

• 2025 [1]
• 2023 [1]
• 2022 [2]
• 2021 [2]
• 2020 [1]
• 2018 [3]
• 更多

学科主题

• 生物催化与转化::生... [1]

筛选

浏览/检索结果: 共26条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Pharmacokinetics, mass balance, and metabolism of [14C]SAF-189s, a potent anaplastic lymphoma kinase/c-ROS proto-oncogene 1 inhibitor in humans: Metabolism potentially affected by interaction of cytochrome P450 enzymes and intestinal microbiota 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 9, 页码: 14 作者:  Yang, Ming;  Diao, Lei;  Yan, Shu;  Tan, Yan;  Liu, Donghui   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/12/04 [C-14]SAF-189s  SAF-189s metabolism and pharmacokinetics  Non-small cell lung cancer  ALK/ROS1 inhibitor  Intestinal flora  P450 enzymes   Continuous measurements in North China and culture experiments reveal the potential of leaf n-alkane carbon isotopes in paleoclimate studies 期刊论文  OAI收割 GLOBAL AND PLANETARY CHANGE, 2023, 卷号: 228, 页码: 12 作者:  Shi, Minrui;  Wang, Guoan;  Guo, Zhengtang;  Han, Jiamao;  Dong, Wanlin   |  收藏  |  浏览/下载：83/0  |  提交时间：2024/01/02 Leaf n-alkane carbon isotopes (delta C-13(alk))  Long-term investigation  Coefficient of delta(13)Calk vs. precipitation  Paleoprecipitation reconstruction  Reconstruction of pCO(2) at PETM   Coexistence of a Novel NBAS-ALK, EML4-ALK Double-Fusion in a Lung Adenocarcinoma Patient With LM and Response to Ensartinib 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17 作者:  Xu, X.;  Li, N.;  Fan, Y.   |  收藏  |  浏览/下载：125/0  |  提交时间：2022/12/23 ALK  non-small cell lung cancer (NSCLC)  leptomeningeal metastases (LM)   Novel HIVEP1-ALK fusion in a patient with lung adenocarcinoma demonstrating sensitivity to alectinib: a case report 期刊论文  OAI收割 TRANSLATIONAL LUNG CANCER RESEARCH, 2022, 卷号: 11 作者:     |  收藏  |  浏览/下载：153/0  |  提交时间：2022/12/22 Non-small cell lung cancer (NSCLC)  HIVEP1-ALK  alectinib  intergenic region (IGR)  case report   A long-term investigation of the variation in leaf wax n-alkanes responding to climate on Dongling Mountain, north China 期刊论文  OAI收割 QUATERNARY INTERNATIONAL, 2021, 卷号: 592, 页码: 67-79 作者:  Shi, Minrui;  Han, Jiamao;  Wang, Guoan;  Wang, Jia;  Han, Yaowen   |  收藏  |  浏览/下载：165/0  |  提交时间：2021/10/25 Total n-alkane concentration (Sigma alk)  Average chain length (ACL)  Carbon preference index (CPI)  Living plants  Climatic factors  Long-term investigation   Quality of Life and Subgroup Analysis in a Phase 3 Randomized Study of Ensartinib vs Crizotinib in ALK-Positive NSCLC Patients: eXalt3. 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2021, 卷号: 16 作者:  Selvaggi, G.;  Wu, Y.;  Wang, Z.;  Wu, G.;  Poddubskaya, E.   |  收藏  |  浏览/下载：190/0  |  提交时间：2021/05/17 ALK  NSCLC  ensartinib   Phase III Randomized Study of Ensartinib vs Crizotinib in Anaplastic Lymphoma Kinase (ALK) POSITIVE NSCLC Patients: eXalt3 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15 作者:  Selvaggi, G.;  Wakelee, H. A.;  Mok, T.;  Wu, Y. -L.;  Reck, M.   |  收藏  |  浏览/下载：185/0  |  提交时间：2020/11/30 ALK plus NSCLC  ensartinib  Crizotinib   Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86 作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin   |  收藏  |  浏览/下载：231/0  |  提交时间：2019/01/08 Heat shock protein 90 (Hsp90)  Tyrosine kinase ALK  Dual inhibitor  Drug resistance  Antiproliferative activity   Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 386-397 作者:  Geng, Kaijun;  Xia, Zongjun;  Ji, Yinchun;  Zhang, Ruisi (Ruthy);  Sun, Deqiao   |  收藏  |  浏览/下载：190/0  |  提交时间：2019/01/08 ALK  G1202R mutant  Drug resistance  2,4-Diarylaminopyrimidine  Resorcinol   Pharmacologic characterization of CT-711, a novel dual inhibitor of ALK and c-Met 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2018, 卷号: 8, 期号: 8, 页码: 1541-1550 作者:  Wang, Lei;  Gao, Mingzhao;  Tong, Mengya;  Xie, Chengying;  He, Ye   |  收藏  |  浏览/下载：189/0  |  提交时间：2019/01/08 CT-711  ALK  c-Met  crizotinib  antitumor activity  pharmacokinetics