中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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机构
上海药物研究所 [2]
上海生物化学与细胞生... [2]
合肥物质科学研究院 [2]
自动化研究所 [1]
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OAI收割 [7]
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期刊论文 [7]
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2020 [1]
2019 [2]
2018 [1]
2015 [1]
2014 [1]
2013 [1]
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学科主题
Biochemist... [1]
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Engagement Enhancement Based on Human-in-the-Loop Optimization for Neural Rehabilitation
期刊论文
OAI收割
FRONTIERS IN NEUROROBOTICS, 2020, 卷号: 14, 页码: 11
作者:
Wang, Jiaxing
;
Wang, Weiqun
;
Ren, Shixin
;
Shi, Weiguo
;
Hou, Zeng-Guang
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/01/06
human-in-the-loop optimization
EEG based neural engagement
sEMG based muscle activation
tracking accuracy
neural rehabilitation
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:
Yan, Yan
;
Zhou, X. Edward
;
Novick, Scott J.
;
Shaw, Simon J.
;
Li, Yingwu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
AMP-activated kinase (AMPK)
AMP
hydrogen exchange mass spectrometry
X-ray crystallography
phosphorylation
activation loop phosphorylation
ADaM site
CBS3
R734
R739
metabolic disorder
energy sensor
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models
期刊论文
OAI收割
CANCER LETTERS, 2019, 页码: 105-114
作者:
Lu, Tingting
;
Chen, Cheng
;
Wang, Aoli
;
Jiang, Zongru
;
Qi, Ziping
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/14
cKIT T670I mutant
Activation loop mutants
Drug resistance
Structure and Physiological Regulation of AMPK
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 11
作者:
Yan, Yan
;
Zhou, X. Edward
;
Xu, H. Eric
;
Melcher, Karsten
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08
energy metabolism
AMPK
activation loop
AID
-linker
-linker
CBS
LKB1
CaMKK2
RIM
Advances in The Research of P53 Pulses
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2015, 卷号: 42
-
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/26
DNA-DAMAGE RESPONSE
P53-MDM2 FEEDBACK LOOP
CELL-FATE
SINGLE CELLS
REGULATORY NETWORK
DYNAMICS
DEATH
OSCILLATIONS
ACTIVATION
THRESHOLD
P53 pulses
DNA damage
p53-Mdm2 negative feedback loop
dynamics
threshold
cell fate
Structural insights into regulatory mechanisms of MO25-mediated kinase activation
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2014, 卷号: 186, 期号: 2, 页码: 224-233
作者:
Hao, Q
;
Feng, M
;
Shi, ZB
;
Li, CC
;
Chen, M
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/07/22
MO25
Germinal center kinases
alpha C helix
Activation-loop
Lysine-glutamate ion pair
Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
期刊论文
OAI收割
FASEB JOURNAL, 2013, 卷号: 27, 期号: 1, 页码: 42006
作者:
Ding, JP
;
Wang, JC
;
Zhong, C
;
Wang, F
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/07/22
activation loop
hydrophobic motif
mammalian target of rapamycin (mTOR) signalling
phosphorylation
ribosomal protein subunit 6 kinase 1 (S6K1)
zinc finger