中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
近代物理研究所 [17]
上海药物研究所 [10]
合肥物质科学研究院 [4]
上海营养与健康研究所 [3]
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OAI收割 [41]
iSwitch采集 [2]
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期刊论文 [38]
会议论文 [4]
学位论文 [1]
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2024 [1]
2023 [1]
2022 [2]
2021 [3]
2020 [2]
2019 [3]
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Biochemist... [2]
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粒子物理与原子核物理 [1]
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Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer
期刊论文
OAI收割
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:
Cheng, Yanan
;
Dong, Li
;
Bu, Dechao
;
Han, Lei
;
Zhao, Yi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/20
HBOC
breast cancer
optical genome mapping
structural variation
BRCA1/2
chromothripsis
Review: Predictive approaches to breast cancer risk
期刊论文
OAI收割
HELIYON, 2023, 卷号: 9, 期号: 11, 页码: 9
作者:
Huang, Shuai
;
Xu, Jun Tao
;
Yang, Mei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/20
Breast cancer
Risk factors
BRCA1/2
Polygenic risk scores
Artificial intelligence
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:
Kayumov, Muzaffar
;
Jia, Li
;
Pardaev, Azizbek
;
Song, Shan-Shan
;
Mirzaakhmedov, Sharafitdin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/03/21
PARP1
Olaparib
Alantolactone
Syntheticlethality
BRCA1/2mutant
Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial
期刊论文
OAI收割
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:
Liu, Jihong
;
Yin, Rutie
;
Wu, Lingying
;
Zhu, Jianqing
;
Lou, Ge
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2022/05/05
BRCA mutation
China
olaparib
ovarian cancer
PARP inhibitor
High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer
期刊论文
OAI收割
BREAST CANCER, 2021
作者:
Zhu, Liang
;
Pan, Jia-Ni
;
Qian, Ziliang
;
Ye, Wei-Wu
;
Wang, Xiao-Jia
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/09/06
CIN
TP53
BRCA1
LPWGS
Breast cancer
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9
作者:
Li, Meng-Zhu
;
Meng, Tao
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Ma, Lan-Ping
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
G-quadruplex stabilizer
MTR-106
BRCA-deficiency
PARP inhibitor
DNA damage
Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells
期刊论文
OAI收割
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:
Wu, Xiaochen
;
Li, Qiqi
;
Zhang, Fan
;
Wang, Lijun
;
Wang, Jun
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/04/21
PARP inhibitor
BRCA
Pancreatic cancer
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+
作者:
Chen, Hua-Dong
;
Guo, Ne
;
Song, Shan-Shan
;
Chen, Chuan-Huizi
;
Miao, Ze-Hong
  |  
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2020/12/24
PARP inhibitors resistance
BRCA2
COX-2
BIRC3
apoptotic resistance
USP9X stabilizes BRCA1 and confers resistance to DNA-damaging agents in human cancer cells
期刊论文
OAI收割
CANCER MEDICINE, 2019, 卷号: 8, 期号: 15, 页码: 6730-6740
作者:
Lu, Qin
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
BRCA1
breast cancer
deubiquitinase
PARP inhibitor
USP9X