机构

• 长春应用化学研究所 [4]
• 上海药物研究所 [3]
• 金属研究所 [2]
• 过程工程研究所 [1]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2019 [1]
• 2018 [1]
• 2013 [2]
• 2012 [2]
• 2011 [1]
• 2010 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318 作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei   |  收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01 beta-amyloid cleaving enzyme  binding selectivity  MSMD  hierarchical clustering analysis  MM-GBSA   Effect of microenvironment on beta-site amyloid precursor protein cleaving enzyme 1 expression in PC12 Cells 期刊论文  OAI收割 Journal of Shanghai Jiaotong University .Medical Science, 2018, 卷号: 38, 期号: 9, 页码: 1005-1012 作者:  Yang Huanqing;  He Xiang;  Du Xiaoguang;  Xiao Shifu;  Wang Tao   |  收藏  |  浏览/下载：139/0  |  提交时间：2019/01/08 Alzheimer's disease  microenvironment  PC12 cell  beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)  amyloid-beta peptide (Abeta)   Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction   Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu   |  收藏  |  浏览/下载：16/0  |  提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction   A Peptide Binding to the beta-Site of APP Improves Spatial Memory and Attenuates A beta Burden in Alzheimer's Disease Transgenic Mice 期刊论文  OAI收割 PLOS ONE, 2012, 卷号: 7, 期号: 11, 页码: 文献号: e48540 作者:  Yang, Shi-gao;  Wang, Shao-wei;  Zhao, Min;  Zhang, Ran;  Zhou, Wei-wei 收藏  |  浏览/下载：27/0  |  提交时间：2013/10/11 AMYLOID PRECURSOR PROTEIN  CLEAVING ENZYME-1 BACE1  LONG-TERM POTENTIATION  SINGLE-CHAIN ANTIBODY  GAMMA-SECRETASE  MOUSE MODEL  THERAPEUTIC TARGET  ALPHA-SECRETASE  CELL BIOLOGY  IN-VITRO   A label-free, G-quadruplex DNAzyme-based fluorescent probe for signal-amplified DNA detection and turn-on assay of endonuclease 期刊论文  OAI收割 biosensors & bioelectronics, 2012, 卷号: 34, 期号: 1, 页码: 100-105 Zhou ZX; Du Y; Zhang LB; Dong SJ 收藏  |  浏览/下载：30/0  |  提交时间：2013/05/22 LINKED-IMMUNOSORBENT-ASSAY  PEROXIDASE-ACTIVITY  RESTRICTION ENDONUCLEASES  MOLECULAR BEACONS  CATALYTIC DNA  CLEAVING DNA  HYBRIDIZATION  ENZYME  CLEAVAGE  COMPLEX   Bifunctional Colorimetric Oligonucleotide Probe Based on a G-Quadruplex DNAzyme Molecular Beacon 期刊论文  OAI收割 analytical chemistry, 2011, 卷号: 83, 期号: 23, 页码: 8871-8876 Zhang LB; Zhu JB; Li T; Wang EK 收藏  |  浏览/下载：21/0  |  提交时间：2012/06/07 PEROXIDASE-ACTIVITY  TELOMERASE ACTIVITY  CATALYTIC DNA  CLEAVING DNA  HYBRIDIZATION  PROTEINS  THROMBIN  ACID  SELECTION  ENZYME   2,2',4'-Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice 期刊论文  OAI收割 JOURNAL OF NEUROCHEMISTRY, 2010, 卷号: 114, 期号: 2, 页码: 374-385 作者:  Zhu, Zhiyuan;  Li, Chenjing;  Wang, Xu;  Yang, Zhengyi;  Chen, Jing   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 Alzheimer's disease  amyloid-beta  inhibitor  transgenic mice  trihydroxychalcone  beta-site amyloid precursor protein-cleaving enzyme 1 (beta-secretase)   Investigation of 3,3 ',5,5 '-tetramethylbenzidine as colorimetric substrate for a peroxidatic DNAzyme 期刊论文  OAI收割 analytica chimica acta, 2009, 卷号: 651, 期号: 2, 页码: 234-240 Li BL; Du Y; Li T; Dong SJ 收藏  |  浏览/下载：21/0  |  提交时间：2010/05/27 CATALYTIC DNA  CLEAVING DNA  COMPLEX  ENZYME  LABEL  THROMBIN  ASSAY   Enhanced catalytic DNAzyme for label-free colorimetric detection of DNA 期刊论文  OAI收割 chemical communications, 2007, 期号: 41, 页码: 4209-4211 Li T; Dong SJ; Wang EK 收藏  |  浏览/下载：198/3  |  提交时间：2010/07/13 TELOMERASE ACTIVITY  PEROXIDASE-ACTIVITY  CLEAVING DNA  ENZYME  COMPLEX  CLEAVAGE