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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海神经科学研究所 [18]
上海药物研究所 [10]
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期刊论文 [60]
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The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-45
作者:
M Song
;
D Chen
;
S P Yu
  |  
收藏
  |  
浏览/下载:251/0
  |  
提交时间:2017/07/24
Skf 96365
Trpc Channel
Glioblastoma
Calcium
na+/ca2+ Exchanger
Cell Cycle
Cell Death
Amlodipine inhibits Synaptotagmin-4's oncogenic activity on gastric cancer proliferation by targeting calcium signaling
期刊论文
OAI收割
FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 卷号: 24, 期号: 3, 页码: 14
作者:
Huang, Wen
;
Yang, Shuo
;
Deng, Minying
;
Luo, Rongkui
;
Liang, Huaiyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/22
Gastric cancer
synaptotagmin-4
Calcium ion channel
Mitogen-activated protein kinase signaling pathway
Amlodipine
Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238
作者:
He Jinyan
;
Tian Fuyun
;
Wu Qingqing
;
Zheng Yueming
;
Chen Yuting
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/10/17
propellane
voltage-gated calcium channel
alpha 2 delta subunit
synthesis
bioactivity
structure-activity relationship
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:
Shen,Meiling
;
Li,Lingfeng
;
Li,Yue
;
Gu,Xi
;
Bai,Longhui
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/07/22
TRPC5
Inhibitors
Virtual screening
Ca 2+channel
CHANNELS
IDENTIFICATION
PERMEABILITY
CALCIUM
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:
Munikishore,Rachakunta
;
Liu,Rui
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Nian,Yin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/07/22
Buxus alkaloid
Structural modification
T -type calcium channel
Analgesic activity
Docking analysis
Structure -activity relationship study
BUXOZINE-C
SEMPERVIRENS
RING
CONSTITUTION
Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:
Zhang, Yuanwen
;
Zheng, Yueming
;
Wu, Qingqing
;
Tian, Fuyun
;
Ma, Chuanjun
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/04/10
Voltage-gated calcium channel
alpha 2 delta subunit
gamma-aminobutyric acid
Mirogabalin
Neuropathic pain
Structure-activity relationship
先导化合物设计与开发
学位论文
OAI收割
: 中国科学院大学, 2022
作者:
Munikishore Rachakunta
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/05/14
Buxus alkaloids
Buxus alkaloids
Cyclovirobuxine-D
Cyclovirobuxine-D
Synthesis, Calcium channel inhibitors
Synthesis, Calcium channel inhibitors
SAR studies
SAR studies
Anti-cardiovascular agents.
Anti-cardiovascular agents.
T-型钙通道天然活性分子挖掘及其在治疗疼痛中的应用
学位论文
OAI收割
: 中国科学院大学, 2022
作者:
李松谕
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/05/14
T-型钙通道,PPAP类化合物,黄酮类化合物
Key words: T-type calcium channel, PPAP, isoprenylated flavonoids
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel
期刊论文
OAI收割
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
作者:
Hu,Guilin
;
Dong,Ding
;
Du,Shuzong
;
Peng,Xingrong
;
Wu,Mingkun
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2022/04/02
Coffea arabica L
Roasted coffee
Coffee diterpenoid
Cafestol
Kahweol
T-type Ca2+ channels
Ca(v)3.1 low voltage-gated Ca2+ channel
Ca(v)3.1 inhibitors
CALCIUM-CHANNELS
CAFESTOL
KAHWEOL
PHYSIOLOGY
ESTERS
NOMENCLATURE
PHARMACOLOGY
APOPTOSIS
FURANS
Review of Voltage-gated Calcium Channel alpha 2 delta Subunit Ligands for the Treatment of Chronic Neuropathic Pain and Insight into Structure-activity Relationship (SAR) by Pharmacophore Modeling
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2022, 卷号: 29, 期号: 30, 页码: 5097-5112
作者:
Chen, Yuting
;
Wu, Qingqing
;
Jin, Zhengsheng
;
Qin, Yanlan
;
Meng, Fancui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/11
Voltage-gated calcium channel
alpha 2 delta subunit
neuropathic pain
structure-activity relationship (SAR)
pharmacophore modeling
gabapentinoids