中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [482]
昆明植物研究所 [92]
过程工程研究所 [84]
生态环境研究中心 [81]
大连化学物理研究所 [79]
化学研究所 [47]
更多
采集方式
OAI收割 [1471]
iSwitch采集 [29]
内容类型
期刊论文 [1365]
学位论文 [113]
会议论文 [18]
SCI/SSCI论文 [3]
专著 [1]
发表日期
2023 [40]
2022 [77]
2021 [90]
2020 [77]
2019 [95]
2018 [127]
更多
学科主题
Pharmacol... [30]
Chemistry [24]
生命有机化学 [21]
Chemistry... [20]
Biochemis... [16]
Chemistry... [16]
更多
筛选
浏览/检索结果:
共1500条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Comprehensively assessing priority odorants emitted from swine slurry combining nontarget screening with olfactory threshold prediction
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 917, 页码: 170428
作者:
Cheng, Yuan
;
Chen, Tongbin
;
Zheng, Guodi
;
Yang, Junxing
;
Yu, Bao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/08
Priority pollutants
Volatile organic compounds
Odor
Structure-odor relationship
Machine learning
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/04/09
Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:
Yang, Wenjiao
;
Gong, Xudong
;
Sun, Haiguo
;
Wu, Chunhui
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
CB2R agonist
5-HT1AR agonist
CB1R antagonist
Antidepressant
Anxiolytic
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
;
Osman, Ezzat E. A.
;
Wang, Xiao-Juan
;
Choo, Yeun-Mun
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Benzothiozinone derivatives with anti-tubercular Activity-Further side chain investigation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 11
作者:
Wu, Xiaomei
;
Wang, Wenxin
;
Stelitano, Giovanni
;
Riabova, Olga
;
Wang, Bin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Anti -tubercular activity
DprE1 inhibitor
Benzothiazinone derivatives
Structure activity relationship
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Design, Synthesis, and Anti-tuberculosis Activity of Streptomycin Derivatives
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 卷号: 21, 期号: 4, 页码: 738-748
作者:
Zhang, Yinyong
;
Zhao, Wenhao
;
Yang, Yushe
;
Zhou, Xianli
;
Guo, Bin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/06
Multidrug-resistant
hydrazine
hydrazide
sulfonyl hydrazide
siderophore
synthesis
anti-tuberculosis activity
Conversion of biochar into sulfonate-bearing solid acids used for the hydrolysis of tylosin: the effect of aromaticity and degree of condensation
期刊论文
OAI收割
BIOCHAR, 2023, 卷号: 5, 期号: 1, 页码: 88
作者:
Xie, Qianqian
;
Yang, Xiao
;
Sarkar, Binoy
;
Dou, Xiaomin
;
Withana, Piumi Amasha
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/04
Biochar upgrading
Sulfonation
Hydrolytic mitigation
Tylosin removal
Biochar-based solid acids