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Chinese Academy of Sciences Institutional Repositories Grid
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Insight into chemical basis of traditional Chinese medicine based on the state-of-the-art techniques of liquid chromatography-mass spectrometry 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1469-1492
作者:  
Yu, Yang;  Yao, Changliang;  Guo, De-an
  |  收藏  |  浏览/下载:61/0  |  提交时间:2021/08/17
High-Throughput In Vitro Gene Expression Profile to Screen of Natural Herbals for Breast Cancer Treatment 期刊论文  OAI收割
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:  
Kui,Ling;  Kong,Qinghua;  Yang,Xiaonan;  Pan,Yunbing;  Xu,Zetan
  |  收藏  |  浏览/下载:86/0  |  提交时间:2022/04/02
基于深度学习的舌象特征分析 期刊论文  OAI收割
计算机科学, 2020, 卷号: 47, 期号: 11, 页码: 148
作者:  
李渊彤;  罗裕升;  朱珍民
  |  收藏  |  浏览/下载:2/0  |  提交时间:2024/05/20
Characterization and discrimination of steroidal saponins in Tribulus terrestris L. and its three different aerial parts by chemical profiling with chemometrics analysis 期刊论文  OAI收割
JOURNAL OF SEPARATION SCIENCE, 2018, 卷号: 41, 期号: 22
作者:  
Qi, Peng;  Zheng, Yuanyuan;  Shen, Yao;  Wang, Jianwei;  Bi, Qirui
  |  收藏  |  浏览/下载:91/0  |  提交时间:2019/01/08
Identification of Ophiocordyceps sinensis and Its Artificially Cultured Ophiocordyceps Mycelia by Ultra-Performance Liquid Chromatography/Orbitrap Fusion Mass Spectrometry and Chemometrics 期刊论文  OAI收割
MOLECULES, 2018, 卷号: 23, 期号: 5
作者:  
Zhang, P;  Li, SN;  Li, J;  Wei, F;  Cheng, XL
  |  收藏  |  浏览/下载:58/0  |  提交时间:2018/12/29
Investigation into the mechanism of Eucommia ulmoides Oliv. based on a systems pharmacology approach 期刊论文  OAI收割
journal of ethnopharmacology, 2014, 卷号: 151, 期号: 1, 页码: 452-460
作者:  
Li, Yan;  Han, Chunxiao;  Wang, Jinghui;  Xiao, Wei;  Wang, Zhenzhong
收藏  |  浏览/下载:35/0  |  提交时间:2015/11/17
A dynamic multiple reaction monitoring method for the multiple components quantification of complex traditional Chinese medicine preparations: Niuhuang Shangqing pill as an example 期刊论文  OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2013, 卷号: 1294, 页码: 58-69
作者:  
Liang, Jian;  Wu, Wan-ying;  Sun, Guo-xiang;  Wang, Dan-dan;  Hou, Jin-jun
  |  收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:42/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Simultaneous determination of Six alkaloids in phellodendron amurense by high-performance liquid chromatography 期刊论文  OAI收割
Acta Chromatographia, 2013, 卷号: 25, 期号: 2, 页码: 275-285
作者:  
Li CD(李彩东);  Liu Y(刘勇);  Shi YP(师彦平);  Shi YP(师彦平)
收藏  |  浏览/下载:29/0  |  提交时间:2013/12/10
Simultaneous determination of huperzine A and huperzine B in different parts of Huperzia serrata from different habitats by HPLC 期刊论文  OAI收割
Chinese Journal of Pharmaceutical Analysis, 2012, 卷号: 32, 期号: 9, 页码: 1541
作者:  
Yuan Jingquan;  Zhou Xiaolei;  Wang Shuo;  Yan Zhigang;  Feng Shixin
  |  收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08