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浏览/检索结果: 共189条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11 作者:  Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo   |  收藏  |  浏览/下载：42/0  |  提交时间：2025/08/20 SARS-CoV-2  3CL(pro) inhibitors  Thioamide derivatives  Spiropyrrolidine derivatives  Nirmatrelvir  HCoV-OC43  Antiviral  Metabolic stability   Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：17/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:     |  收藏  |  浏览/下载：43/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   Structure-guided design and photochemical synthesis of new carbamo (dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 114, 页码: 9 作者:  Yin, De-Hang;  Xin, Jie;  Chen, Shizhao;  Li, Shuai-Shuai;  Li, Zi-Ying   |  收藏  |  浏览/下载：59/0  |  提交时间：2024/12/11 SARS-CoV-2  Disulfiram  Carbamo(dithioperoxo)thioates  Photochemistry  3CL pro   Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5 作者:  Shen, Wen   |  收藏  |  浏览/下载：55/0  |  提交时间：2024/10/21 COVID-19  SARS-CoV-2 3CL pro inhibitor  Drug design  Antiviral activities   Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan   |  收藏  |  浏览/下载：54/0  |  提交时间：2023/10/17 Covid-19  3CL protease inhibitor  SARS-CoV-2 viral load  Alleviation of COVID-19 symptoms   Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Zhu, Mengwei;  Fu, Tiantian;  You, Mengyuan;  Cao, Junyuan;  Yang, Hanxi   |  收藏  |  浏览/下载：43/0  |  提交时间：2023/10/17 COVID-19  SARS-CoV-2  3CL protease  Nirmatrelvir  Peptidomimetic inhibitors   Squeezing More Past Knowledge for Online Class-Incremental Continual Learning 期刊论文  OAI收割 IEEE/CAA Journal of Automatica Sinica, 2023, 卷号: 10, 期号: 3, 页码: 722-736 作者:  Da Yu;  Mingyi Zhang;  Mantian Li;  Fusheng Zha;  Junge Zhang   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/03/02 Catastrophic forgetting  class-incremental learning  continual learning (CL)  experience replay   Migration Mechanism of Lattice Oxygen: Conversion of CO2 to CO Using NiFe2O4 Spinel Oxygen Carrier in Chemical Looping Reactions 期刊论文  OAI收割 CATALYSTS, 2022, 卷号: 12, 期号: 10, 页码: 20 作者:  Song, Da;  Lin, Yan;  Zhao, Kun;  Huang, Zhen;  He, Fang   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/11/14 chemical looping (CL)  oxygen carrier (OC)  CO2 splitting  lattice oxygen  NiFe2O4   Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 209, 页码: 8 作者:  Zhu, Dafu   |  收藏  |  浏览/下载：62/0  |  提交时间：2022/06/15 SARS-CoV-2  3CL protease  Native MS  Traditional Chinese medicine  Natural product