中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
采集方式
OAI收割 [5]
内容类型
期刊论文 [5]
发表日期
2024 [1]
2020 [2]
2019 [1]
2002 [1]
学科主题
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Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 2, 页码: 6
作者:
Zhu, Yingli
;
Qian, Jie
;
Yu, Kunqian
;
Hou, Jing
;
Ma, Yeshuo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/01/26
Theranostic probe
Artificial intelligence
Conformational restriction
Fluorescence restoration
Design strategy
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 22, 页码: 6
作者:
Wang, Zhenkang
;
Ma, Chunhua
;
Wang, Yujie
;
Xiao, Qiang
;
Xu, Chenghui
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Gentisides
Neurotrophic activity
Isosteric replacement
Conformational restriction
PC 12 cells
Enantiospecific synthesis of all four Stereoisomers of novel bicyclic arylacetamides as kappa-Opioid agonists
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2002, 卷号: 20, 期号: 10, 页码: 1073-1079
作者:
Long, YQ
;
Mou, QY
;
Qiu, DP
;
Wu, RQ
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
kappa-Opioid receptor agonist
bicyclic arylacetamide
conformational restriction
enantiospecific synthesis