中国科学院机构知识库网格
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The effectiveness of the DNA-V program on reducing anxiety among Chinese adolescents: Outcomes of the face-to-face and web-based versions 期刊论文  OAI收割
JOURNAL OF SCHOOL PSYCHOLOGY, 2024, 卷号: 106, 页码: 19
作者:  
Shao, Siyang;  Zhang, Ye;  Yang, Mo;  Li, Chieh;  Zhao, Ruonan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/10/14
The effect of DNA-V model intervention on learning behaviors and stress in Chinese adolescents: A randomized controlled trial 期刊论文  OAI收割
JOURNAL OF CONTEXTUAL BEHAVIORAL SCIENCE, 2023, 卷号: 30, 页码: 181-190
作者:  
Liu, Yinghui;  Chen, Yue;  Liu, Zidi;  Zhang, Ye;  Wu, Mengxue
  |  收藏  |  浏览/下载:19/0  |  提交时间:2024/01/02
初中生心理灵活性干预方案开发及其对生涯适应力的影响 学位论文  OAI收割
中国科学院心理研究所: 中国科学院心理研究所, 2021
作者:  
刘子荻
  |  收藏  |  浏览/下载:43/0  |  提交时间:2022/01/25
青少年自我中心对抑郁的影响及干预研究 学位论文  OAI收割
中国科学院心理研究所: 中国科学院心理研究所, 2020
作者:  
吴梦雪
  |  收藏  |  浏览/下载:52/0  |  提交时间:2021/04/08
基于多个扩增子的DNA metabarcoding技术探究黄海微型真核浮游植物多样性 期刊论文  OAI收割
环境科学, 2019, 卷号: 40, 期号: 9, 页码: 4052-4060
作者:  
张莉;  张远;  林佳宁;  王书平
  |  收藏  |  浏览/下载:16/0  |  提交时间:2020/06/02
Diterpenoids from Isodon species: an update 期刊论文  OAI收割
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  
Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
  |  收藏  |  浏览/下载:34/0  |  提交时间:2017/10/23
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:36/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
以精子为载体转基因大菱鲆的电脉冲方法 专利  OAI收割
专利类型: 发明, 专利号: CN200510046451.X, 申请日期: 2006-11-22, 公开日期: 2006-11-22
作者:  
谭训刚
收藏  |  浏览/下载:15/0  |  提交时间:2014/08/04
Interactions with ATP, DNA cleavage and anti-tumor activities of complexes with anions [Mo(V)O-2(O2C6H4)(2)](3-),[Mo(V)(0.5)W(VI)(0.5)O-2(O2C6H4)(2)](2.5-) and [W(VI)O-2(O2C6H4)(2)](2-) 期刊论文  OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2005, 卷号: 23, 期号: 6, 页码: 781-785
作者:  
Lu, XM;  Jiang, L;  Mao, XA;  Ye, CH;  Lu, JF
收藏  |  浏览/下载:15/0  |  提交时间:2015/07/15