中国科学院机构知识库网格系统: 检索

浏览/检索结果: 共4条，第1-4条

帮助

条数/页：排序方式：
	The Second-generation of Highly Potent Hepatitis C Virus (HCV) NS3/4A Protease Inhibitors: Evolutionary Design Based on Tailor-made Amino Acids, Synthesis and Major Features of Bio-activity 期刊论文 OAI收割 CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 30, 页码: 4493-4554 作者: Wang, Shuni; Wang, Yibing; Wang, Jiang; Sato, Tatsunori; Izawa, Kunisuke \| 收藏 \| 浏览/下载：51/0 \| 提交时间：2019/01/08 Hepatitis C virus (HCV) pandemic direct-acting antiviral agents (DAAs) NS3/4A protease inhibitor tailor-made amino acids structure-activity relationship (SAR) asymmetric synthesis ring-closing metathesis (RCM)
	Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 12, 页码: 2900-2906 作者: Cheng, Yu; Shen, Jian; Peng, Run-Ze; Wang, Gui-Feng; Zuo, Jian-Ping \| 收藏 \| 浏览/下载：37/0 \| 提交时间：2019/01/08 HCV NS5B polymerase 2-Alkyl quinolone 1,6-Naphthyridine-4,5-dione Non-nucleoside inhibitor Direct acting antiviral Allosteric site
	2-Aryl-3-carbonylquinolones: Design, Synthesis and Biological Evaluation of Novel HCV NS5B Polymerase Inhibitors 期刊论文 OAI收割 ACTA CHIMICA SINICA, 2014, 卷号: 72, 期号: 8, 页码: 906-913 作者: Wang Shenfeng; Lin Jianping; He Peilan; Zuo Jianping; Long Yaqiu \| 收藏 \| 浏览/下载：17/0 \| 提交时间：2019/01/08 HCV NS5B polymerase 2-substituted quinolone-3-carboxylic acid non-nucleoside inhibitor direct acting antiviral allosteric site
	2芳基3羰基喹诺酮新型hcvns5b多聚酶抑制剂的设计合成和活性评估期刊论文 OAI收割化学学报, 2014, 卷号: 72, 期号: 8, 页码: 906 作者: 王沈丰; 林建平; 何佩岚; 左建平; 龙亚秋 \| 收藏 \| 浏览/下载：19/0 \| 提交时间：2020/07/01 HEPATITIS-C VIRUS HIV-1 INTEGRASE INHIBITORS INFECTION NUCLEOTIDE SCAFFOLD SOFOSBUVIR DISCOVERY LEDGF/P75 ACIDS HCV NS5B polymerase 2-substituted quinolone-3-carboxylic acid non-nucleoside inhibitor direct acting antiviral allosteric site