中国科学院机构知识库网格系统: 检索

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	IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文 OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者: Yao, Mingyue; Yan, Wenzhong; Wang, Yafang; Zhao, Yu; Xu, Xiaowei \| 收藏 \| 浏览/下载：8/0 \| 提交时间：2025/04/01 Acute myeloid leukemia HDAC inhibitor FLT3-ITD mutation DNA damage response Synergistic effect Drug resistance
	Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文 OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者: Lai, Mengzhen; Zhang, Tao; Chen, Hao; Song, Peiran; Tong, Linjiang \| 收藏 \| 浏览/下载：123/0 \| 提交时间：2023/04/10 fourth-generation EGFR inhibitor EGFRC797S mutation NSCLC drug resistance small molecular inhibitor
	Discovery of novel heteroaryl alkynes for highly potent KITD816V cells inhibition to treat gastrointestinal stromal tumors 期刊论文 OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 10, 页码: 4004-4007 作者: Xie, Zhicheng; Li, Lin; Guo, Yihao; Zhang, Mi; Chen, Taiwen \| 收藏 \| 浏览/下载：34/0 \| 提交时间：2022/12/13 KITD816V cells Mutation Drug resistance Gastrointestinal stromal tumors
	BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation 期刊论文 OAI收割 THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135 作者: Yin, Weimin; Zhao, Yuge; Kang, Xuejia; Zhao, Pengfei; Zhao, Xuhong \| 收藏 \| 浏览/下载：96/0 \| 提交时间：2020/07/01 brain targeting delivery tumor-associated macrophage non-small cell lung cancer (NSCLC) drug resistance tyrosine kinase inhibitors (TKI) EGFR T790M mutation
	Drug resistance mutation profiles of the drug-na < ve and first-line regimen-treated hiv-1-infected population of suzhou, china 期刊论文 iSwitch采集 Virologica sinica, 2017, 卷号: 32, 期号: 4, 页码: 271-279 作者: Li, Tingting; Qian, Feng; Yuan, Ting; Xu, Weilu; Zhu, Li 收藏 \| 浏览/下载：69/0 \| 提交时间：2019/05/08 Hiv-1 Drug resistance mutation First-line regimen China