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浏览/检索结果: 共9条，第1-9条 帮助

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A review on pharmacology and toxicology of Elephantopus scaber Linn. 期刊论文  OAI收割
NATURAL PRODUCT RESEARCH, 2014, 卷号: 28, 期号: 11, 页码: 819-830
Hiradeve, Sachin M.; Rangari, Vinod D.
收藏  |  浏览/下载：28/0  |  提交时间：2016/05/12
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载：44/0  |  提交时间：2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Synthesis of oleanolic acid saponins mimicking components of Chinese folk medicine Di Wu 期刊论文  OAI收割
CARBOHYDRATE RESEARCH, 2009, 卷号: 344, 期号: 10, 页码: 1153-1158
Huang, Xing; Cheng, Shuihong; Du, Yuguo; Bing, Feihong
收藏  |  浏览/下载：20/0  |  提交时间：2015/08/07
A new alkaloid from Solanum cathayanum 期刊论文  OAI收割
CHINESE CHEMICAL LETTERS, 2008, 卷号: 19, 期号: 1, 页码: 68-70
作者:  Wang, JZ;  Cheng, F;  Li, X;  horsedog@163.com
  |  收藏  |  浏览/下载：17/0  |  提交时间：2011/07/03
An 18-norspirostanol saponin with inhibitory action against COX-2 production from the underground part of Trillium tschonoskii 期刊论文  OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 卷号: 55, 期号: 4, 页码: 679-681
作者:  kzou@ctgu.edu.cn;  Wang, JZ;  Zou, K;  Zhang, YM;  Liu, C
  |  收藏  |  浏览/下载：25/0  |  提交时间：2011/07/03
Effect of total phenolics from Laggera alata on acute and chronic inflammation models 期刊论文  OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2006, 卷号: 108, 期号: 2, 页码: 243-250
作者:  Wu, Yihang;  Zhou, Changxin;  Song, Liyan;  Li, Xiangping;  Shi, Shuyun
  |  收藏  |  浏览/下载：33/0  |  提交时间：2011/11/24
Molecular authentication of the traditional Tibetan medicinal plant Swertia mussotii 期刊论文  OAI收割
PLANTA MEDICA, 2006, 卷号: 72, 期号: 13, 页码: 1223-1226
作者:  Xue, Chun-Ying;  Li, De-Zhu;  Lu, Jin-Mei;  Yang, Jun-Bo;  Liu, Jian-Quan
  |  收藏  |  浏览/下载：25/0  |  提交时间：2011/12/06
Molecular authentication of the traditional Tibetan medicinal plant Swertia mussotii 期刊论文  OAI收割
planta medica, 2006, 卷号: 72, 期号: 13, 页码: 1223-1226
作者:  Xue, Chun-Ying;  Li, De-Zhu;  Lu, Jin-Mei;  Yang, Jun-Bo;  Liu, Jian-Quan
收藏  |  浏览/下载：28/0  |  提交时间：2009/12/08
Variation of active constituents of an important Tibet folk medicine Swertia mussotii Franch. (Gentianaceae) between artificially cultivated and naturally distributed 期刊论文  OAI收割
journal of ethnopharmacology, 2005, 卷号: 98, 期号: 1-2, 页码: 31-35
作者:  Yang, HL;  Ding, CX;  Duan, YW;  Liu, HQ
收藏  |  浏览/下载：35/0  |  提交时间：2009/12/09