机构

• 上海药物研究所 [4]
• 昆明植物研究所 [3]
• 海洋研究所 [2]
• 近代物理研究所 [2]
• 水生生物研究所 [1]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [14]
• iSwitch采集 [1]

内容类型

• 期刊论文 [15]

发表日期

• 2018 [5]
• 2016 [2]
• 2013 [2]
• 2012 [1]
• 2011 [1]
• 2008 [1]
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学科主题

• Developmen... [1]
• Medicine, ... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 11 作者:  Jin, Qinghao;  Guo, Mingquan;  Li, Xun;  Qiu, Zidong;  Chen, Guilin   |  收藏  |  浏览/下载：30/0  |  提交时间：2018/12/29 colon cancer  Toddalia asiatica Lam.  G2/M arrest  apoptosis  reactive oxygen species   Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Li, Xun;  Qiu, Zidong;  Jin, Qinghao;  Chen, Guilin;  Guo, Mingquan   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 colon cancer  Toddalia asiatica Lam.  G2/M arrest  apoptosis  reactive oxygen species   Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots 期刊论文  OAI收割 CHEMOSPHERE, 2018, 页码: 586-594 作者:  Liu, Wan;  Cao, Xia;  Wang, Hetong;  Zhuang, Defeng   |  收藏  |  浏览/下载：47/0  |  提交时间：2018/09/10 Arabidopsis  Cd stress  Cell cycle  G2 phase arrest  DNA damage  DNA mismatch repair   Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文  OAI收割 CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481 作者:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang   |  收藏  |  浏览/下载：50/0  |  提交时间：2018/05/08 Rabdocoestin b  G2/m Phase Arrest  Apoptosis  Cytotoxicity  Esophageal Squamous Cell Carcinoma   Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文  OAI收割 CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621 作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang   |  收藏  |  浏览/下载：122/0  |  提交时间：2018/07/16 Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC   p21 is Responsible for Ionizing Radiation-induced Bypass of Mitosis 期刊论文  OAI收割 BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2016, 卷号: 29, 页码: 484-493 作者:  Zhang Xu Rui;  Liu Yong Ai;  Sun Fang;  Li He;  Lei Su Wen   |  收藏  |  浏览/下载：23/0  |  提交时间：2018/05/31 G2/M transition  DNA damage  Ionizing radiation  G2 arrest   FS-108,an Hsp90 inhibitor,impairs survival and motility of oncogene addicted cancer cells 期刊论文  OAI收割 Chinese Pharmacological Bulletin, 2016, 卷号: 32, 期号: 10, 页码: 1357-1363 作者:  Ping Fangfang;  Wang Yueqin;  Zhang Minmin;  Shi Feng;  Chen Danqi   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Hsp90  caspase-3  Hsp90  EBC-1 and A375 cells  G_2/M arrest  apoptosis  Caspase-3  migration   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：43/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   Asperolide A, a Marine-Derived Tetranorditerpenoid, Induces G2/M Arrest in Human NCI-H460 Lung Carcinoma Cells, Is Mediated by p53-p21 Stabilization and Modulated by Ras/Raf/MEK/ERK Signaling Pathway 期刊论文  OAI收割 MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 316-331 作者:  Lv, Cuiting;  Sun, Wenxia;  Sun, Haofen;  Wei, Shanjian;  Chen, Ruohua 收藏  |  浏览/下载：29/0  |  提交时间：2014/07/17 asperolide A  G2/M arrest  p53-p21  Ras/Raf/MEK/ERK signaling pathway   A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma 期刊论文  OAI收割 EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 卷号: 237, 期号: 4, 页码: 442-450 作者:  Wang, Cuicui;  Liu, Ming;  Cheng, Linyou;  Wei, Jianteng;  Wu, Ning 收藏  |  浏览/下载：27/0  |  提交时间：2013/09/24 Meretrix meretrix Linnaeus  antitumor polypeptide  non-small-cell lung carcinoma  G(2)/M phase arrest  apoptosis