中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [7]
生物物理研究所 [1]
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期刊论文 [13]
学位论文 [1]
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2020 [1]
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Modulating effects of RAMPs on signaling profiles of the glucagon receptor family
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 2, 页码: 637-650
作者:
Shao, Lijun
;
Chen, Yan
;
Zhang, Shikai
;
Zhang, Zhihui
;
Cao, Yongbing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
G protein-coupled receptor
Glucagon receptor family
Receptor activity-modulating protein
Signaling
Allosteric modulation
GPCR-RAMP interaction
Receptor pharmacology
Ligand selectivity
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
Computational insights into the G-protein-biased activation and inactivation mechanisms of the mu opioid receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 1, 页码: 154-164
作者:
Cheng, Jian-xin
;
Cheng, Tao
;
Li, Wei-hua
;
Liu, Gui-xia
;
Zhu, Wei-liang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
G-protein-coupled receptor
mu opioid receptor
molecular dynamics
activation switch
G-protein bias
beta-arrestin signaling
TRV130
BU72
beta-FNA
naltrexone
computationalinsightsintothegproteinbiasedactivationandinactivationmechanismsoftheopioidreceptor
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 1, 页码: 154
作者:
Cheng Jianxin
;
Cheng Tao
;
Li Weihua
;
Liu Guixia
;
Zhu Weiliang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
G-protein-coupled receptor
μ opioid receptor
molecular dynamics
activation switch
G-protein bias
β-arrestin signaling
TRV130
BU72
β-FNA
naltrexone
Emerging insights into heterotrimeric G protein signaling in plants
期刊论文
OAI收割
JOURNAL OF GENETICS AND GENOMICS, 2016, 卷号: 43, 期号: 8, 页码: 495-502
作者:
Xu Quan
;
Zhao Mingzhu
;
Wu Kun
;
Fu Xiangdong
;
Liu Qian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/02/02
GTPASE-ACTIVATING PROTEINS
ALPHA-SUBUNIT GPA1
ARABIDOPSIS-THALIANA
GAMMA-SUBUNIT
BINDING PROTEIN
BETA-SUBUNIT
CELL-PROLIFERATION
COUPLED RECEPTORS
MOLECULAR-CLONING
GRAIN LENGTH
G protein signaling
Non-canonical G gamma subunits
DEP1
GS3
Yield potential
Canonical transient receptor potential 4 and its small molecule modulators
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 1, 页码: 39-47
作者:
Fu Jie
;
Gao ZhaoBing
;
Shen Bing
;
Zhu, Michael X.
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
TRPC4 channel
non-selective cation channel
G protein coupled receptors
small molecular modulators
G proteins
excitation
contraction
Ca2+ signaling
全氟化合物与脂肪酸靶蛋白的相互作用及干扰效应研究
学位论文
OAI收割
博士, 北京: 中国科学院研究生院, 2014
张连营
收藏
  |  
浏览/下载:249/0
  |  
提交时间:2015/06/16
全氟化合物
肝脏型脂肪酸结合蛋白
过氧化物酶体增殖剂激活受体
G-蛋白偶联受体40
信号通路
perfluorinated compounds
liver fatty acid binding protein
peroxisome proliferator-activated receptor γ
G protein coupled receptor 40
signaling pathway.
Cholesterol level influences opioids signaling in cell models and analgesia in mice and humans
期刊论文
OAI收割
Journal of lipid Research, 2012, 卷号: 53, 期号: 6, 页码: 1153-1162
作者:
Hui Zheng
;
Haibo Zou
;
Xiaopeng Liu
;
Ji Chu
;
Yali Zhou
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2018/12/13
Anesthesia
Camp Signaling
g Protein Coupling
Simvastatin
Misfolded G beta is recruited to cytoplasmic dynein by Nudel for efficient clearance
期刊论文
OAI收割
CELL RESEARCH, 2012, 卷号: 22, 期号: 7, 页码: 1140-1154
作者:
Wan, YH
;
Yang, ZY
;
Guo, J
;
Zhang, QG
;
Zeng, LY
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/07/22
protein degradation
dynein-mediated transport
G beta
protein misfolding
signaling