中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [4]
昆明植物研究所 [3]
海洋研究所 [2]
近代物理研究所 [2]
水生生物研究所 [1]
武汉植物园 [1]
更多
采集方式
OAI收割 [14]
_filter
_filter
_filter
筛选
浏览/检索结果:
共14条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Lasiokaurin Regulates PLK1 to Induce Breast Cancer Cell G2/M Phase Block and Apoptosis
期刊论文
OAI收割
JOURNAL OF CANCER, 2024, 卷号: 15, 期号: 8, 页码: 2318-2328
作者:
Liu, Zhengrui
;
Wang, Jia
;
Xie, Siman
;
Zhang, Benteng
;
Yuan, Yan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/22
Lasiokaurin
breast cancer
G2/M phase block
apoptosis
PLK1
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 11
作者:
Jin, Qinghao
;
Guo, Mingquan
;
Li, Xun
;
Qiu, Zidong
;
Chen, Guilin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2018/12/29
colon cancer
Toddalia asiatica Lam.
G2/M arrest
apoptosis
reactive oxygen species
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Xun
;
Qiu, Zidong
;
Jin, Qinghao
;
Chen, Guilin
;
Guo, Mingquan
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
colon cancer
Toddalia asiatica Lam.
G2/M arrest
apoptosis
reactive oxygen species
Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
作者:
Wang, Jingnan
;
Zhang, Zhirong
;
Che, Yun
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2018/05/08
Rabdocoestin b
G2/m Phase Arrest
Apoptosis
Cytotoxicity
Esophageal Squamous Cell Carcinoma
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:
Wang, Jing-Nan
;
Zhang, Zhi-Rong
;
Che, Yun
;
Yuan, Zu-Yang
;
Lu, Zhi-Liang
  |  
收藏
  |  
浏览/下载:125/0
  |  
提交时间:2018/07/16
Acetyl-macrocalin B
reactive oxygen species
p38 MAPK
apoptosis
Chk1
Chk2
G2
M phase arrest
NSCLC
p21 is Responsible for Ionizing Radiation-induced Bypass of Mitosis
期刊论文
OAI收割
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2016, 卷号: 29, 页码: 484-493
作者:
Zhang Xu Rui
;
Liu Yong Ai
;
Sun Fang
;
Li He
;
Lei Su Wen
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2018/05/31
G2/M transition
DNA damage
Ionizing radiation
G2 arrest
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)
one of the major components isolated from the traditional
Chinese medicine Rubia yunnanensis
exhibited inhibitory activity on the proliferation of several
human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay
and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle
arrest in human cervical carcinoma HeLa cells. Further
MTA was found to induce apoptosis of HeLa cells
through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and
release of cytochrome c into the cytosol
which caused the cleavage of caspase and poly(ADP-ribose)
polymerase and finally triggered the apoptosis. Furthermore
the p53/p21/Cdc2-cyclin B1 signaling was
found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of
cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused
the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of
R. yunnanensis
a folk anti-cancer herb used in Yunnan
China.
Asperolide A, a Marine-Derived Tetranorditerpenoid, Induces G2/M Arrest in Human NCI-H460 Lung Carcinoma Cells, Is Mediated by p53-p21 Stabilization and Modulated by Ras/Raf/MEK/ERK Signaling Pathway
期刊论文
OAI收割
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 316-331
作者:
Lv, Cuiting
;
Sun, Wenxia
;
Sun, Haofen
;
Wei, Shanjian
;
Chen, Ruohua
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2014/07/17
asperolide A
G2/M arrest
p53-p21
Ras/Raf/MEK/ERK signaling pathway
文蛤多肽的分离纯化及抗肿瘤机制研究
学位论文
OAI收割
博士, 北京: 中国科学院研究生院, 2011
王翠翠
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2012/06/24
文蛤
抗肿瘤多肽
G2/M 期阻滞
细胞凋亡