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浏览/检索结果: 共13条，第1-10条 帮助

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Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文  OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 11
作者:  Jin, Qinghao;  Guo, Mingquan;  Li, Xun;  Qiu, Zidong;  Chen, Guilin
  |  收藏  |  浏览/下载：30/0  |  提交时间：2018/12/29
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文  OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Li, Xun;  Qiu, Zidong;  Jin, Qinghao;  Chen, Guilin;  Guo, Mingquan
  |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文  OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
作者:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang
  |  收藏  |  浏览/下载：50/0  |  提交时间：2018/05/08
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文  OAI收割
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang
  |  收藏  |  浏览/下载：122/0  |  提交时间：2018/07/16
p21 is Responsible for Ionizing Radiation-induced Bypass of Mitosis 期刊论文  OAI收割
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2016, 卷号: 29, 页码: 484-493
作者:  Zhang Xu Rui;  Liu Yong Ai;  Sun Fang;  Li He;  Lei Su Wen
  |  收藏  |  浏览/下载：23/0  |  提交时间：2018/05/31
FS-108,an Hsp90 inhibitor,impairs survival and motility of oncogene addicted cancer cells 期刊论文  OAI收割
Chinese Pharmacological Bulletin, 2016, 卷号: 32, 期号: 10, 页码: 1357-1363
作者:  Ping Fangfang;  Wang Yueqin;  Zhang Minmin;  Shi Feng;  Chen Danqi
  |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载：43/0  |  提交时间：2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Asperolide A, a Marine-Derived Tetranorditerpenoid, Induces G2/M Arrest in Human NCI-H460 Lung Carcinoma Cells, Is Mediated by p53-p21 Stabilization and Modulated by Ras/Raf/MEK/ERK Signaling Pathway 期刊论文  OAI收割
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 316-331
作者:  Lv, Cuiting;  Sun, Wenxia;  Sun, Haofen;  Wei, Shanjian;  Chen, Ruohua
收藏  |  浏览/下载：29/0  |  提交时间：2014/07/17
A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma 期刊论文  OAI收割
EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 卷号: 237, 期号: 4, 页码: 442-450
作者:  Wang, Cuicui;  Liu, Ming;  Cheng, Linyou;  Wei, Jianteng;  Wu, Ning
收藏  |  浏览/下载：27/0  |  提交时间：2013/09/24
C1q-like inhibits p53-mediated apoptosis and controls normal hernatopoiesis during zebrafish embryogenesis 期刊论文  OAI收割
DEVELOPMENTAL BIOLOGY, 2008, 卷号: 319, 期号: 2, 页码: 273-284
作者:  Mei, Jie;  Zhang, Qi-Ya;  Li, Zhi;  Lin, Shuo;  Gui, Jian-Fang
收藏  |  浏览/下载：88/3  |  提交时间：2010/10/13