中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
金属研究所 [2]
上海生物化学与细胞生... [1]
烟台海岸带研究所 [1]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2017 [2]
2012 [3]
2011 [3]
2010 [1]
2009 [1]
学科主题
Biochemist... [1]
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Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152
作者:
Wang, Zhengyu
;
Shi, Xiaofan
;
Zhang, Huan
;
Yu, Liang
;
Cheng, Yanhua
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
Hypoglycemia
Dyslipidemia
Glucokinase activators
N-Thiazol-2-yl-benzamides
Molecular cloning, expression and characterisation of glucokinase gene from the mixotrophic green alga Chlorella kessleri
期刊论文
OAI收割
PHYCOLOGIA, 2017, 卷号: 56, 期号: 5, 页码: 477-486
作者:
Chen, Jun
;
Cui, Hongli
;
Hou, Yanhua
;
Cui, Yulin
;
Wang, Yifan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2018/01/10
Biochemical Characterisation
Chlorella Kessleri
Expression Profiles
Gene Cloning
Glucokinase
Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 58, 页码: 624-639
作者:
Zhang, Lei
;
Chen, Xiaojie
;
Liu, Jun
;
Zhu, Qingzhang
;
Leng, Ying
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Glycogen phosphorylase inhibitors
Glucokinase activators
Type 2 diabetes
Dual-target-directed
Hybrid
Investigation on the oxidation of aryl oxiranylmethanols and the synthesis of 2-aryl-N-thiazolyl-oxirane-2-carboxamides as gincokinase activators
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2012, 卷号: 53, 期号: 35, 页码: 4738-4742
作者:
Ye, Na
;
Xu, Xiangtao
;
Li, Fuying
;
Ning, Mengmeng
;
Liu, Zhiqing
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
Arylacetamides
Glucokinase activators
Ruthenium-catalyzed
Oxo-rearrangement
Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 9, 页码: 2982-2991
作者:
Mao, Weiwei
;
Ning, Mengmeng
;
Liu, Zhiqing
;
Zhu, Qingzhang
;
Leng, Ying
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Type 2 diabetes (T2D)
Glucokinase activator
Benzamide derivatives
Privileged-fragment-merging
Aminothiazole
Leptospira interrogans encodes an ROK family glucokinase involved in a cryptic glucose utilization pathway
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2011, 卷号: 43, 期号: 8, 页码: 618-629
作者:
Zhang, Q
;
Zhang, YY
;
Zhong, Y
;
Ma, J
;
Peng, NQ
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2015/07/22
Leptospira interrogans
glucokinase
glucose utilization
Design, synthesis and biological evaluation of novel glucokinase activators
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2011, 卷号: 22, 期号: 1, 页码: 73-76
作者:
Li Yong Qiang
;
Zhang Yu Liang
;
Hu Sheng Quan
;
Wang Yu Ling
;
Song Hong Rui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/02/02
DISCOVERY
POTENT
Diabetes
Glucokinase activators
Benzamide derivatives
Design, synthesis and biological evaluation of novel glucokinase activators
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2011, 卷号: 22, 期号: 1, 页码: 73-76
作者:
Li Yong Qiang
;
Zhang Yu Liang
;
Hu Sheng Quan
;
Wang Yu Ling
;
Song Hong Rui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/02/02
DISCOVERY
POTENT
Diabetes
Glucokinase activators
Benzamide derivatives
Design, synthesis, and pharmacological evaluation of N-(4-mono and 4,5-disubstituted thiazol-2-yl)-2-aryl-3-(tetrahydro-2H-pyran-4-yl) propanamides as glucokinase activators
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 卷号: 18, 期号: 11, 页码: 3875-3884
作者:
Li, Fuying
;
Zhu, Qingzhang
;
Zhang, Yi
;
Feng, Ying
;
Leng, Ying
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Type 2 diabetes (T2D)
Glucokinase activator
Arylacetamide
Aminothiazole
Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 20, 页码: 7301-7312
作者:
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Glucokinase (GK) activators
Glycogen phosphorylase (GP) inhibitors
Type 2 diabetes
Dual action