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浏览/检索结果: 共25条，第1-10条 帮助

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Discovery of Highly Potent and Selective Thyroid Hormone Receptor βAgonists for the Treatment of Nonalcoholic Steatohepatitis 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3284-3300
作者:  Hu, Liuyu;  Gu, Yipei;  Liang, Ju;  Ning, Mengmeng;  Yang, Junli
  |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 242, 页码: 114697
作者:  Han, Fanghui;  Ning, Mengmeng;  Wang, Kai;  Gu, Yipei;  Qu, Hui
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21
Discovery of a Potent and Selective Degrader for USP7 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 卷号: 61, 期号: 33, 页码: e202204395
作者:  Pei, Yuan;  Fu, Jingfeng;  Shi, Yunkai;  Zhang, Mengmeng;  Luo, Guanghao
  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/21
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice 期刊论文  OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:  Zhao, Zhuohui;  Deng, Zhen-Tao;  Huang, Suling;  Ning, Mengmeng;  Feng, Ying
  |  收藏  |  浏览/下载：21/0  |  提交时间：2022/08/16
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
  |  收藏  |  浏览/下载：33/0  |  提交时间：2021/11/04
Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid 期刊论文  OAI收割
METABOLITES, 2021, 卷号: 11, 期号: 6, 页码: 374
作者:  Zhu, Nanlin;  Huang, Suling;  Zhang, Qingli;  Zhao, Zhuohui;  Qu, Hui
  |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/21
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying
  |  收藏  |  浏览/下载：18/0  |  提交时间：2020/12/21
Discovery of Highly Polar beta-Homophenylalanine Derivatives as Nonsystemic Intestine-Targeted Dipeptidyl Peptidase IV Inhibitors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 23, 页码: 10919-10925
作者:  Huang, Fubao;  Ning, Mengmeng;  Wang, Kai;  Liu, Jia;  Guan, Wenbo
  |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice 期刊论文  OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 99, 页码: 45-56
作者:  Huang, Suling;  Ma, Shanyao;  Ning, Mengmeng;  Yang, Wenji
  |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
Design, synthesis and structure activity relationship studies of GPR40 agonists containing amide linker 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 175-194
作者:  Chen, Tingting;  Ning, Mengmeng;  Ye, Yangliang;  Wang, Kai;  Leng, Ying
  |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08