机构

• 上海药物研究所 [8]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2025 [1]
• 2023 [1]
• 2018 [1]
• 2016 [3]
• 2015 [1]
• 2013 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from Hypericum patulum 期刊论文  OAI收割 PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10 作者:  Huang, Jin-Chang;  Jia, Xin-Yu;  Lv, Yi-Fan;  Xu, Hong-Hong;  Han, Ming   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01 Hypericum patulum  Hypericaceae  Meroterpenoids  Hyperpatins A-H  Death-associated protein kinase-related  apoptosis-inducing kinase 2  Glucose-stimulated insulin secretion   Discovery of orally effective and safe GPR40 agonists by incorporating a chiral, rigid and polar sulfoxide into 8-position to the carboxylic acid 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115267 作者:  Chen, Cheng;  Guo, Shi-Meng;  Sun, Yuanjun;  Li, He;  Hu, Nan   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/27 GPR40  Glucose-stimulated insulin secretion  Type 2 diabetes mellitus  Lipophilicity  Liver safety  Three-in-one pharmacophore  2-(phenylsulfinyl)acetic acid   ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia 期刊论文  OAI收割 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264 作者:  Zhou, Tingting;  Du, Mengfan;  Zhao, Tong;  Quan, Lingling;  Zhu, Zhiyuan   |  收藏  |  浏览/下载：111/0  |  提交时间：2019/01/08 beta cell  apoptosis  glucose-stimulated insulin secretion  T2DM   GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 23, 页码: 5603-5612 作者:  Chen, Cheng;  Li, He;  Long, Ya-Qiu   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 GPR40  Glucose-stimulated insulin secretion  Type 2 diabetes  FFA1  Biased agonism   Advances in Small-Molecule GPR40 Agonists for Treatment of Type 2 Diabetes Mellitus 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 36, 期号: 4, 页码: 736-743 作者:  Li He;  Long Yaqiu   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 type II diabetes mellitus  GPR40  agonists  glucose-stimulated insulin secretion  phenylpropanoic acid   advancesinsmallmoleculegpr40agonistsfortreatmentoftype2diabetesmellitus 期刊论文  OAI收割 chinesejournaloforganicchemistry, 2016, 卷号: 36, 期号: 4, 页码: 736 作者:  Li H(李鹤);  Long YQ(龙亚秋)   |  收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 1 FFA1/GPR40 AGONIST  IN-VITRO  DISCOVERY  POTENT  ACIDS  IDENTIFICATION  OPTIMIZATION  CELLS  type II diabetes mellitus  GPR40  agonists  glucose-stimulated insulin secretion  phenylpropanoic acid   BBT improves glucose homeostasis by ameliorating beta-cell dysfunction in type 2 diabetic mice 期刊论文  OAI收割 JOURNAL OF ENDOCRINOLOGY, 2015, 卷号: 224, 期号: 3, 页码: 327-341 作者:  Yao, Xin-gang;  Xu, Xin;  Wang, Gai-hong;  Lei, Min;  Quan, Ling-ling   |  收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 beta-cell dysfunction  glucose-stimulated insulin  secretion (GSIS)  beta-cell death  glucose homeostasis  Journal of Endocrinology   Natural product vindoline stimulates insulin secretion and efficiently ameliorates glucose homeostasis in diabetic murine models 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2013, 卷号: 150, 期号: 1, 页码: 285-297 作者:  Yao, Xin-gang;  Chen, Fanglei;  Li, Ping;  Quan, Lingling;  Chen, Jing   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Vindoline  Type 2 diabetes  Glucose-stimulated insulin secretion  beta-cell dysfunction