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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
广州生物医药与健康研... [2]
大连化学物理研究所 [1]
上海生物化学与细胞生... [1]
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OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2023 [1]
2022 [3]
2021 [2]
2020 [5]
2019 [1]
2018 [4]
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学科主题
Biochemist... [2]
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Tail engagement of arrestin at the glucagon receptor
期刊论文
OAI收割
NATURE, 2023, 页码: 21
作者:
Chen, Kun
;
Zhang, Chenhui
;
Lin, Shuling
;
Yan, Xinyu
;
Cai, Heng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Effects of site-directed mutagenesis of GLP-1 and glucagon receptors on signal transduction activated by dual and triple agonists
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
Darbalaei, Sanaz
;
Chang, Ru-lue
;
Zhou, Qing-tong
;
Chen, Yan
;
Dai, An-tao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/09/30
glucagon-like peptide-1 receptor
glucagon receptor
dual and triple agonist
cAMP
pERK1/2
unimolecular polypharmacology
Structural basis of peptidomimetic agonism revealed by small-molecule GLP-1R agonists Boc5 and WB4-24
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 20, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Qingtong
;
Li, Yang
;
Chen, Li-Nan
;
Zhang, Zi-Chen
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/09/30
glucagon-like peptide-1 receptor
type 2 diabetes mellitus
cryoelectron microscopy
peptidomimetic agonism
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Zhao, Fenghui
;
Zhou, Qingtong
;
Cong, Zhaotong
;
Hang, Kaini
;
Zou, Xinyu
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/06/15
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
G protein-coupled receptors: structure- and function-based drug discovery
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27
作者:
Yang, Dehua
;
Zhou, Qingtong
;
Labroska, Viktorija
;
Qin, Shanshan
;
Darbalaei, Sanaz
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:
Darbalaei, Sanaz
;
Yuliantie, Elita
;
Dai, Antao
;
Chang, Rulue
;
Zhao, Peishen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/21
G protein-coupled receptor
Glucagon-like peptide-1 receptor
Glucagon receptor
Biased agonism
Unimolecular dual agonist
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxypheny1)-N-phenylpiperidine-1-carboxamide as novel potent analgesic
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:
Huang, Huoming
;
Wang, Wenli
;
Xu, Xuejun
;
Zhu, Chen
;
Wang, Yujun
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Selective MOR agonists
Antinociception
Analgesic
Opioids
Molecular mechanism