中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
上海生物化学与细胞生... [1]
合肥物质科学研究院 [1]
昆明动物研究所 [1]
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OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2025 [1]
2022 [1]
2021 [1]
2018 [1]
2017 [2]
2015 [1]
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学科主题
Pharmacolo... [1]
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IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19
作者:
Yao, Mingyue
;
Yan, Wenzhong
;
Wang, Yafang
;
Zhao, Yu
;
Xu, Xiaowei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Acute myeloid leukemia
HDAC inhibitor
FLT3-ITD mutation
DNA damage response
Synergistic effect
Drug resistance
The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKK? and overcomes gefitinib resistance in non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 8, 页码: 1172-1192
作者:
He, Ting
;
Gao, Yinglei
;
Fang, Yanfen
;
Zhang, Yangming
;
Zhang, Shuwei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/21
HDAC inhibitor
c-Met
IKK?
NSCLC
gefitinib
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Exploratory clinical study of chidamide, an oral subtype-selective histone deacetylase inhibitor, in combination with exemestane in hormone receptor-positive advanced breast cancer
期刊论文
OAI收割
CHINESE JOURNAL OF CANCER RESEARCH, 2018, 卷号: 30
-
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/10/26
PHASE-I
POSTMENOPAUSAL WOMEN
HDAC INHIBITOR
MULTICENTER
ENTINOSTAT
TAMOXIFEN
CS055/HBI-8000
RESISTANCE
LETROZOLE
TRIAL
Advanced breast cancer
hormone receptor-positive
chidamide
exemestane
Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 8, 页码: 830-834
作者:
Lu, Dong
;
Yan, Juan
;
Wang, Lang
;
Liu, Hongchun
;
Zeng, Limin
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/01/08
Dual c-Met/HDAC inhibitor
hybrid
designed multiple ligand (DML)
Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 128, 页码: 293-299
作者:
Wang, Jiang
;
Su, Mingbo
;
Li, Tingting
;
Gao, Anhui
;
Yang, Wei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
HDAC inhibitor
Anti-proliferation
Western blot
Thienopyrimidine
Structure-activity relationship
Design, synthesis and biological evaluation of colchicine derivatives as novel tubulin and histone deacetylase dual inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 95, 页码: 127-135
作者:
Zhang, Xuan
;
Kong, Yannan
;
Zhang, Jie
;
Su, Mingbo
;
Zhou, Yubo
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Colchicine
Dual inhibitor
HDAC
Tubulin
Hybrid
Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees
期刊论文
OAI收割
EMBO REPORTS, 2011, 卷号: 12, 期号: 3, 页码: 238-243
作者:
Spannhoff, Astrid
;
Kim, Yong Kee
;
Raynal, Noel J. -M.
;
Gharibyan, Vazganush
;
Su, Ming-Bo
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Apis mellifera
epigenetic
HDAC inhibitor
phenotypic plasticity
royal jelly
ERK1/2 activation plays important roles in the opposite effects of Trichostatin A in non-cancer and cancer cells
期刊论文
OAI收割
TOXICON, 2011, 卷号: 57, 期号: 6, 页码: 932-937
作者:
Zhang, Y
;
Yu, GY
;
Wang, DM
;
Hu, Y
;
Lei, WW
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2015/07/22
HDAC inhibitor
TSA
Apoptosis
ERK1/2
Non-cancer cells
Cancer cells
ERK1/2 activation plays important roles in the opposite effects of Trichostatin A in non-cancer and cancer cells
期刊论文
OAI收割
TOXICON, 2011, 卷号: 57, 期号: 6, 页码: 932-937
作者:
Zhang Y
;
Yu GY
;
Wang DM
;
Hu Y
;
Lei WW[*]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2011/06/13
HDAC inhibitor
TSA
Apoptosis
ERK1/2