中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [54]
合肥物质科学研究院 [19]
上海生物化学与细胞... [15]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:
Guo, Huihui
;
Zhang, Xilin
;
Xie, Shangzhi
;
Chen, Tianwei
;
Xie, Dong
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2022/12/22
gefitinib
CD28H
NSCLC
EGFR mutation
The effect of EGFR-TKIs on survival in advanced non-small-cell lung cancer with EGFR mutations: A real-world study
期刊论文
OAI收割
CANCER MEDICINE, 2022
作者:
Yu, Xiaoqing
;
Si, Jinfei
;
Wei, Jingwen
;
Wang, Yanling
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2022/12/23
EGFR-TKIs
non-small cell lung cancer (NSCLC)
real-world study
survival outcome
Ocellatuperoxides A-F, Uncommon Anti-Tumoral gamma-Pyrone Peroxides from a Photosynthetic Mollusk Placobranchus ocellatus
期刊论文
OAI收割
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 14
作者:
Li, Song-Wei
;
Wu, Qihao
;
Xu, Heng
;
Yao, Li-Gong
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/13
photosynthetic mollusk
Placobranchus ocellatus
gamma-pyrone polypropionate
ocellatuperoxides
anti-tumoral activity
Comprehensive landscape of the ST3GAL family reveals the significance of ST3GAL6-AS1/ST3GAL6 axis on EGFR signaling in lung adenocarcinoma cell invasion
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 10, 页码: 17
作者:
Li, Jiaxuan
;
Long, Yiming
;
Sun, Jingya
;
Wu, Jiajun
;
He, Xiao
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/13
lung adenocarcinoma
sialyltransferase
prognostic analysis
ST3GAL6
ST3GAL6-AS1
The HDAC inhibitor GCJ-490A suppresses c-Met expression through IKK? and overcomes gefitinib resistance in non-small cell lung cancer
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 8, 页码: 1172-1192
作者:
He, Ting
;
Gao, Yinglei
;
Fang, Yanfen
;
Zhang, Yangming
;
Zhang, Shuwei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
HDAC inhibitor
c-Met
IKK?
NSCLC
gefitinib
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Zi-tong
;
Wang, Jue
;
Fang, Lei
;
Qian, Xin-di
;
Cai, Ying
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
nanoparticles
molecular targeted therapy
non-small cell lung cancer
dual-responsive
controlled release
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
OAI收割
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Efficacy and safety of anlotinib with and without EGFR-TKIs or immunotherapy in the treatment of elder patients with non-small-cell lung cancer: a retrospective study
期刊论文
OAI收割
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wang, Wenxian
;
Shao, Lan
;
Xu, Yibing
;
Song, Zhengbo
;
Lou, Guangyuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Non-small cell lung cancer
Prognosis
Angiogenesis
Tyrosine kinase inhibitors
Poly(maleic anhydride-alt-1-octadecene)-based bioadhesive nanovehicles improve oral bioavailability of poor water-soluble gefitinib
期刊论文
OAI收割
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2022, 卷号: 48, 期号: 3, 页码: 109-116
作者:
Wang, Guanru
;
Xie, Yaru
;
Qian, Xindi
;
Zhang, Xinyue
;
Shan, Yanqiang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/21
Gefitinib
nanovehicle
oral bioavailability
poorly water soluble drugs
bioadhesive