中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
重庆绿色智能技术研究... [2]
昆明动物研究所 [2]
福建物质结构研究所 [1]
新疆理化技术研究所 [1]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2021 [2]
2020 [2]
2018 [1]
2012 [2]
2011 [3]
学科主题
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Nanopore detects.-radiation inhibited HIV-1 protease activity
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2021, 卷号: 194, 页码: 5
作者:
Li, Minghan
;
Li, Wei
;
Xiao, Yicen
;
Liu, Qianshan
;
Liang, Liyuan
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/11/26
HIV-1 protease
GagPol precursor
Enzyme inactivation
Co-60 gamma-radiation
Nanopore
Predicting HIV-1 Protease Cleavage Sites With Positive-Unlabeled Learning
期刊论文
OAI收割
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 3, 页码: 1-11
作者:
Li, ZF (Li, Zhenfeng)[ 1 ]
;
Hu, L (Hu, Lun)[ 2 ]
;
Tang, ZH (Tang, Zehai)[ 1 ]
;
Zhao, C (Zhao, Cheng)[ 1 ]
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/05/06
HIV-1 protease
cleavage site prediction
positive-unlabeled learning
biased SVM
substrate specificity
Incorporating the Coevolving Information of Substrates in Predicting HIV-1 Protease Cleavage Sites
期刊论文
OAI收割
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 6, 页码: 2017-2028
作者:
Hu, Lun
;
Hu, Pengwei
;
Luo, Xin
;
Yuan, Xiaohui
;
You, Zhu-Hong
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2021/03/01
HIV-1 protease
substrate specificity
coevolving information
cleavage site prediction
Accurate prediction of relative binding affinities of a series of HIV-1 protease inhibitors using semi-empirical quantum mechanical charge
期刊论文
OAI收割
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2020, 页码: 8
作者:
Peng, Cheng
;
Wang, Jinan
;
Xu, Zhijian
;
Cai, Tingting
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
adaptive steered molecular dynamics (ASMD)
binding affinity
HIV-1 protease
semi-empirical quantum mechanics
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling
期刊论文
OAI收割
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:
Chen, Jianzhong
;
Peng, Cheng
;
Wang, Jinan
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
allosteric inhibitor
HIV-1 protease
MM-GBSA
normal mode analysis
REMD
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:
Yan, Jianwei
;
Huang, Ning
;
Li, Shukun
;
Yang, Liu-Meng
;
Xing, Weiqiang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
HIV-1 protease inhibitors
Amprenavir
Darunavir biaryl compounds
Docking study
Synthesis and biological evaluation of novel amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 5, 页码: 1976-1979
作者:
Yan JW
;
Huang N
;
Li SK
;
Yang LM
;
Xing WQ
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2012/03/19
HIV-1 protease inhibitors
Amprenavir
Darunavir biaryl compounds
Docking study
Mangiferin, an Anti-HIV-1 Agent Targeting Protease and Effective against Resistant Strains
期刊论文
OAI收割
MOLECULES, 2011, 卷号: 16, 期号: 5, 页码: 4264-4277
作者:
Wang, Rui-Rui
;
Gao, Yue-Dong
;
Ma, Chun-Hui
;
Zhang, Xing-Jie
;
Huang, Cheng-Gang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
mangiferin
HIV-1
protease
anti-HIV agents
drug resistance
Protonation-Triggered Conversion between Single- and Triple-Stranded Helices with a Visible Fluorescence Change
期刊论文
OAI收割
Angewandte Chemie-International Edition, 2011, 卷号: 50, 期号: 5, 页码: 1149-1153
X. H. Jin
;
J. A. Wang
;
J. K. Sun
;
H. X. Zhang
;
J. Zhang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2012/06/06
fluorescence
helical structures
hydrogen bonds
structural
transformations
viologen
intramolecular charge-transfer
aggregation-induced emission
hiv-1
protease
polymers
coordination
motion
water
oligoresorcinols
oligoamides
transition
Mangiferin, an Anti-HIV-1 Agent Targeting Protease and Effective against Resistant Strains
期刊论文
OAI收割
MOLECULES, 2011, 卷号: 16, 期号: 5, 页码: 4264-4277
作者:
Wang RR
;
Gao YD
;
Ma CH
;
Zhang XJ
;
Huang CG[*]
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2011/06/13
mangiferin
HIV-1
protease
anti-HIV agents
drug resistance