中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共886条,第1-10条 帮助

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Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:  
Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin
  |  收藏  |  浏览/下载:7/0  |  提交时间:2024/03/06
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:  
Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/01/26
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:  
Dong, Sanfeng;  Hu, Ke;  Shi, Yulong;  Wang, Guanli;  Yu, Dandan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/02/19
Cryptotanshinone regulates gut microbiota and PI3K-AKT pathway in rats to alleviate CUMS induced depressive symptoms 期刊论文  OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 169, 页码: 11
作者:  
Bian, Li-hua;  Wang, Si-qi;  Li, Wen-jing;  Li, Jie;  Yin, Yi
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/01/18
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:  
Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/19
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:  
Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/10/17
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway 期刊论文  OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:  
Wang, Yingcong;  Dong, Sanfeng;  Hu, Ke;  Xu, Li;  Feng, Qilin
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/01/26
Integrating serum pharmacochemistry and network pharmacology to reveal the active constituents and mechanism of Corydalis Rhizoma in treating Alzheimer's disease 期刊论文  OAI收割
FRONTIERS IN AGING NEUROSCIENCE, 2023, 卷号: 15, 页码: 20
作者:  
Lyu, Yan;  Wang, Yu;  Guo, Jianyou;  Wang, Yuqing;  Lu, Yifan
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/01/02
The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches 期刊论文  OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:  
Sultan, Rida;  Ahmed, Abrar;  Wei, Li;  Saeed, Hamid;  Islam, Muhammad
  |  收藏  |  浏览/下载:7/0  |  提交时间:2023/12/19
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma 期刊论文  OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:  
Yuan, Hong-Kai;  Li, Bo;  Wu, Leyun;  Wang, Xue-Ling;  Lv, Zhi-Ying
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/03/26