机构

• 上海药物研究所 [1]
• 昆明植物研究所 [1]
• 高能物理研究所 [1]

采集方式

• OAI收割 [2]
• iSwitch采集 [1]

内容类型

• 期刊论文 [3]

发表日期

• 2018 [1]
• 2013 [1]
• 2008 [1]

学科主题

筛选

浏览/检索结果: 共3条，第1-3条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis 期刊论文  iSwitch采集 Iet nanobiotechnology, 2018, 卷号: 12, 期号: 4, 页码: 377-391 作者:  Barabadi, Hamed;  Alizadeh, Ahad;  Ovais, Muhammad;  Ahmadi, Amirhossein;  Shinwari, Zabta Khan 收藏  |  浏览/下载：72/0  |  提交时间：2019/04/23 Reviews  Nanoparticles  Cancer  Nanomedicine  Magnetic particles  Nanomagnetics  Nanofabrication  Cellular biophysics  Bayes methods  Microorganisms  Toxicology  Antibacterial activity  Green nanoparticles  Cancerous cell lines  Normal cell lines  Review  Meta-analysis  Microbial synthesised metallic nanoparticles  Bayesian generalised linear model  Hela cancer cell lines  A549 cancer cell lines  Gram-negative bacteria  Gram-positive bacteria  Cytotoxicity  Anticancer agents  Cancer disease treatment   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：43/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   Apoptosis induction effect of Pinellia extract fraction on cell lines of cervical cancer cultured in vitro 期刊论文  OAI收割 China Journal of Traditional Chinese Medicine and Pharmacy, 2008, 卷号: 23, 期号: 5, 页码: 447-449 作者:  LI Guiling;  GUI Suiqi;  CHEN Songhua;  GE Xiui;  LIN Ligen   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Pinellia extract fraction  Extract  Apoptosis  Cervical cancer  HeLa and CaSki cell lines