中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
昆明植物研究所 [5]
昆明动物研究所 [5]
生物物理研究所 [2]
武汉病毒研究所 [2]
福建物质结构研究所 [1]
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OAI收割 [24]
iSwitch采集 [2]
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期刊论文 [24]
学位论文 [2]
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2022 [1]
2018 [1]
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Biochemist... [2]
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浏览/检索结果:
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A new polysaccharide platform constructs self-adjuvant nanovaccines to enhance immune responses
期刊论文
OAI收割
JOURNAL OF NANOBIOTECHNOLOGY, 2022, 卷号: 20, 期号: 1, 页码: 320
作者:
Chen, Sisi
;
Yang, Liu
;
Ou, Xia
;
Li, Jin-Yu
;
Zi, Cheng-Ting
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/04/30
Polysaccharide
Self-adjuvant
Nanovaccine
SARS-CoV-2
HIV
STRUCTURAL-CHARACTERIZATION
DENDRITIC CELLS
DRUG-DELIVERY
NANOPARTICLES
PARTICLES
CHITOSAN
GLYCOGEN
DESIGN
A new class of HIV-1 inhibitors and the target identification via proteomic profiling
期刊论文
OAI收割
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 11, 页码: 1430-1439
作者:
Ge, Ying-Zi
;
Zhou, Bin
;
Xiao, Ruo-Xuan
;
Yuan, Xiao-Jing
;
Zhou, Hu
  |  
收藏
  |  
浏览/下载:201/0
  |  
提交时间:2019/01/08
ergostane-type steroids
anti-HIV
target identification
PKM2
Interaction between herpesvirus entry mediator and hsv-2 glycoproteins mediates hiv-1 entry of hsv-2-infected epithelial cells
期刊论文
iSwitch采集
Journal of general virology, 2017, 卷号: 98, 期号: 9, 页码: 2351-2361
作者:
Hu, Kai
;
He, Siyi
;
Xiao, Juhua
;
Li, Mei
;
Luo, Sukun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/05/08
Hiv-1
Hsv-2
Herpesvirus entry mediator
Co-infection
Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 133, 页码: 85-96
作者:
Tang, Jing
;
Vernekar, Sanjeev Kumar V.
;
Chen, Yue-Lei
;
Miller, Lena
;
Huber, Andrew D.
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
2-hydroxyisoquinoline-1,3-diones
HIV
RNase H
Reverse transcriptase
Inhibitor
The effects of TRIM5 alpha polymorphism on HIV-2ROD and SIVmac239 replication in PBMCs from Chinese rhesus macaques and Vietnamese-origin cynomolgus macaques
期刊论文
OAI收割
VIROLOGY, 2016, 卷号: 487, 期号: X, 页码: 222-229
作者:
Zhang HL
;
Liu FL
;
Zhuo M
;
Liu XH
;
Zheng YT[*]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2016/07/22
TRIM5 alpha polymorphism
HIV-2ROD
SIVmac239
Chinese-origin rhesus macaques
Vietnamese-origin cynomolgus macaques
Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 162, 页码: 369-376
作者:
Cheng, Bao-Hui
;
Zhou, Xuelin
;
Wang, Yan
;
Chan, Judy Yuet-Wa
;
Lin, Huang-Quan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2015/06/29
SH formula
Atazanavir
Anti-HIV
CYP3A2
Herb-drug interaction
Design, synthesis, and biological evaluation of novel 2-methylpiperazine derivatives as potent CCR5 antagonists
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 5, 页码: 1157-1168
作者:
Hu, Suwen
;
Wang, Zhilong
;
Hou, Tingjun
;
Ma, Xiaodong
;
Li, Jing
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
CCR5 antagonist
Anti-HIV-1 agent
2-Methylpiperazine derivatives
2芳基3羰基喹诺酮新型hcvns5b多聚酶抑制剂的设计合成和活性评估
期刊论文
OAI收割
化学学报, 2014, 卷号: 72, 期号: 8, 页码: 906
作者:
王沈丰
;
林建平
;
何佩岚
;
左建平
;
龙亚秋
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
HEPATITIS-C VIRUS
HIV-1 INTEGRASE INHIBITORS
INFECTION
NUCLEOTIDE
SCAFFOLD
SOFOSBUVIR
DISCOVERY
LEDGF/P75
ACIDS
HCV NS5B polymerase
2-substituted quinolone-3-carboxylic acid
non-nucleoside inhibitor
direct acting antiviral
allosteric site
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 19, 页码: 5963-5972
作者:
Serrao, Erik
;
Xu, Zhong-Liang
;
Debnath, Bikash
;
Christ, Frauke
;
Debyser, Zeger
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
HIV-1
Integrase
LEDGF/p75
5-carbonyl-1H-Imidazole-4-carboxamide
Protein-protein interaction
Antiviral
PDB ID code2B4J
Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 16, 页码: 4935-4952
作者:
Fan, Xing
;
Zhang, Feng-Hua
;
Al-Safi, Rasha I.
;
Zeng, Li-Fan
;
Shabaik, Yumna
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
HIV-1 integrase inhibitors
2,3-Dihydroxybenzamide
Strand transfer
3 '-Process
LEDGF/p75
Chelation