中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [2]
地理科学与资源研究所 [1]
上海生物化学与细胞生... [1]
长春应用化学研究所 [1]
采集方式
OAI收割 [5]
内容类型
期刊论文 [4]
SCI/SSCI论文 [1]
发表日期
2023 [1]
2019 [1]
2017 [1]
2015 [2]
学科主题
Genetics &... [1]
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Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead
期刊论文
OAI收割
GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414
作者:
Li, Hui-yu
;
Qi, Wei-liang
;
Wang, Yu-xiang
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:244/0
  |  
提交时间:2023/10/17
Biomarkers
Covalent KRasG12Cinhibitors
Drug resistance
Human cancers
KRASG12Cmutation
Development and Application of Base Editors
期刊论文
OAI收割
CRISPR JOURNAL, 2019, 卷号: 2, 期号: 2, 页码: 91-104
作者:
Yang, Bei
;
Yang, Li
;
Chen, Jia
;
Chen, Jia
;
,
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/21
CYTOSINE DEAMINATION
DIRECTED EVOLUTION
DNA-POLYMERASES
HUMAN CANCERS
GENOMIC DNA
CRISPR
REPAIR
STRAND
PATHWAY
APOBEC
Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682
作者:
Liu, Shi-en
;
Hu, Jun-chi
;
Zhang, Hao
;
Xu, Pan
;
Wan, Wei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
phosphoglycerate mutase 1 (PGAM1)
human cancers
metabolic target
C-terminal region
conformational changes
molecular dynamics simulation
Association between Changing Mortality of Digestive Tract Cancers and Water Pollution: A Case Study in the Huai River Basin, China
SCI/SSCI论文
OAI收割
2015
作者:
Ren H. Y.
;
Wan, X.
;
Yang, F.
;
Shi, X. M.
;
Xu, J. W.
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2017/11/09
increasing mortality
digestive tract cancers
water pollution
drinking
water safety
Huai River Basin
drinking-water
temporal variations
human health
esophageal
quality
exposure
microcystins
carcinoma
nitrate
surface
Label-free fluorescence turn-on detection of microRNA based on duplex-specific nuclease and a perylene probe
期刊论文
OAI收割
analytica chimica acta, 2015, 卷号: 895, 期号: 37, 页码: 89-94
作者:
Hu,Zhenzhen
;
Chen,Jian
;
Li,Wenying
;
Wang,Yan
;
Li,Yongxin
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2016/05/12
SIGNAL AMPLIFICATION
HUMAN CANCERS
QUANTIFICATION
EXPRESSION
HYBRIDIZATION
STRATEGY
POLYMER
ASSAY
MIRNA