中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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过程工程研究所 [5]
上海药物研究所 [4]
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Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2023, 页码: 10
作者:
Lin, Rongkun
;
Yang, Jie
;
Liu, Ting
;
Wang, Mingyu
;
Ke, Chongrong
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/10/17
CDK9
cyclin T1
degrader
hydrophobic tag
protein degradation
High hydrostatic pressure refolding of highly hydrophobic protein: A case study of recombinant human interferon beta-1b from inclusion bodies
期刊论文
OAI收割
BIOCHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 172, 页码: 9
作者:
Wang, Qi
;
Zhang, Chun
;
Li, Zenglan
;
Guo, Fangxia
;
Zhang, Jing
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/31
High hydrostatic pressure
Refolding
Hydrophobic protein
rhIFN beta-1b
Inclusion bodies
Protein Aggregation and Performance Optimization Based on Microconformational Changes of Aromatic Hydrophobic Regions
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2018, 卷号: 15, 期号: 6, 页码: 2257-2267
作者:
Wen, Lili
;
Lyu, Man
;
Xiao, Huashuai
;
Lan, Hairong
;
Zuo, Zhili
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2018/07/16
Protein Aggregation
Aromatic Hydrophobic Regions
Amine Compounds
Guanidine Compounds
Microconformational Change
Adsorption-associated orientational changes of immunoglobulin G and regulated phagocytosis of Staphylococcus epidermidis
期刊论文
OAI收割
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2018, 卷号: 106, 期号: 11, 页码: 2838-2849
作者:
He, Xiaoyan
;
Hou, Wenjia
;
Liu, Yi
;
Zhang, Botao
;
Li, Hua
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2018/12/04
Protein Adsorption
Human-igg
Adsorbed Antibodies
Bacterial Adhesion
Hydrophobic Teflon
Charged Surfaces
Binding
Biomaterials
Graphite
Behavior
Adsorption-associated orientational changes of immunoglobulin G and regulated phagocytosis of Staphylococcus epidermidis
期刊论文
OAI收割
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2018, 卷号: 106, 期号: 11, 页码: 2838-2849
作者:
He, Xiaoyan
;
Hou, Wenjia
;
Liu, Yi
;
Zhang, Botao
;
Li, Hua
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2018/12/04
Protein Adsorption
Human-igg
Adsorbed Antibodies
Bacterial Adhesion
Hydrophobic Teflon
Charged Surfaces
Binding
Biomaterials
Graphite
Behavior
Extended particle swarm optimisation method for folding protein on triangular lattice
期刊论文
OAI收割
IET SYSTEMS BIOLOGY, 2016, 卷号: 10, 期号: 1, 页码: 30-33
作者:
Guo, Yuzhen
;
Wu, Zikai
;
Wang, Ying
;
Wang, Yong
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/07/30
proteins
molecular biophysics
molecular configurations
particle swarm optimisation
bioinformatics
extended particle swarm optimisation method
triangular lattice
protein structure prediction problem
two-dimensional hydrophobic-polar model
noncompact conformation
amino acid sequence
single point adjustment strategy
protein folding
Directing membrane chromatography to manufacture alpha(1)-antitrypsin from human plasma fraction IV
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2015, 卷号: 1423, 期号: DEC, 页码: 63-70
作者:
Fan, Jinxin
;
Luo, Jianquan
;
Song, Weijie
;
Chen, Xiangrong
;
Wan, Yinhua
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2016/01/18
Membrane chromatography
Plasma protein
alpha(1)-Antitrypsin
Ion-exchange
Hydrophobic interaction
Membrane adsorber
Effect of grafted PEG chain conformation on albumin and lysozyme adsorption: A combined study using QCM-D and DPI
期刊论文
OAI收割
colloids and surfaces b-biointerfaces, 2015, 卷号: 136, 页码: 838-844
作者:
Jin,Jing
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2016/05/12
QUARTZ-CRYSTAL MICROBALANCE
DUAL-POLARIZATION INTERFEROMETRY
SELF-ASSEMBLED MONOLAYERS
AIR-WATER-INTERFACE
PROTEIN ADSORPTION
POLYETHYLENE OXIDE
POLYELECTROLYTE MULTILAYERS
FIBRINOGEN ADSORPTION
HYDROPHOBIC SURFACES
REAL-TIME
Microspheres and Microcapsules for Protein Delivery: Strategies of Drug Activity Retention
期刊论文
OAI收割
CURRENT PHARMACEUTICAL DESIGN, 2013, 卷号: 19, 期号: 35, 页码: 6340-6352
作者:
Wang, Lianyan
;
Liu, Yuan
;
Zhang, Weifeng
;
Chen, Xiaoming
;
Yang, Tingyuan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2015/05/05
Hydrophilic polymer microspheres
hydrophobic polymer microcapsules
protein delivery
activity retention
strategies
The significance of molecular mechanics property to protein evolution
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2013, 卷号: 8, 期号: 1, 页码: 83-91
作者:
Zhang LM
;
Liu X(刘鑫)
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2013/09/09
hydrophobic interaction
protein evolution
mechanics property