中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
上海生物化学与细胞生... [8]
沈阳应用生态研究所 [6]
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期刊论文 [51]
会议论文 [1]
学位论文 [1]
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2023 [2]
2021 [2]
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In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2025, 卷号: 505, 页码: 12
作者:
Gu, Zeyun
;
Chen, Guihua
;
Gao, Nan
;
Yao, Shuo
;
Zhang, Xiaoru
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Trichosanthin
IL2
Hydrogel
Postoperative administration
Cancer immunotherapy
Dendritic cells
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1
期刊论文
OAI收割
THERANOSTICS, 2024, 卷号: 14, 期号: 17, 页码: 6543-6559
作者:
Li, Meiqian
;
Cui, Yangyan
;
Qi, Qi
;
Liu, Jiakuan
;
Li, Jiaxuan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/25
SPOP
bladder cancer
tumor-associated macrophage
STAT3/CCL2/IL-6 axis
VEZF1
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:
Shi, Huanyu
;
Tang, Haotian
;
Li, Yan
;
Chen, Danqi
;
Liu, Tongchao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Cancer immunotherapy
SAR study
HPK1 inhibitors
Quinazoline-2
5-diamine
IL-2 production
Could IL-25 be a potential therapeutic target for intestinal inflammatory diseases?
期刊论文
OAI收割
CYTOKINE & GROWTH FACTOR REVIEWS, 2023, 卷号: 69, 页码: 43-50
作者:
Chen, Jie
;
Wang, Yingshu
;
Shen, Lan
;
Xiu, Yanfeng
;
Wang, Bing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
IL-25
Type-2 immunity
Inflammatory bowel disease
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
OAI收割
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation
期刊论文
OAI收割
bioRxiv : the preprint server for biology, 2021, 卷号: 1, 期号: 1, 页码: 1
作者:
Taiwei Li
;
Adam D. Kenney
;
Helu Liu
;
Guillaume N. Fiches
;
Dawei Zhou
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/09/02
SARS-CoV-2
NF-κB
IL-8
IMPDH2
ribavirin
mycophenolic acid
Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 33, 页码: 127749
作者:
Yang, Bowen
;
Wu, Qian
;
Huan, Xiajuan
;
Wang, Yingqing
;
Sun, Yin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/03/21
TNIK inhibitor
1H-pyrrolo[2,3-b]pyridine
IL-2 secretion inhibitory
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Effect of the complete replacement of dietary fish meal by soybean meal on histopathology and immune response of the hindgut in grass carp (Ctenopharyngodon idellus)
期刊论文
OAI收割
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2020, 卷号: 221, 页码: 9
作者:
Peng, Kai-Song
;
Wu, Nan
;
Cui, Zheng-Wei
;
Zhang, Xiang-Yang
;
Lu, Xiao-Bing
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/05/25
Grass carp
Enteritis
Histopathology
IL-17A/F1
IL-2/15Ra
Ig tau
Functional characterization of interleukin (IL)-22 and its inhibitor, IL-22 binding protein (IL-22BP) in Mandarin fish, Siniperca chuatsi
期刊论文
OAI收割
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2019, 卷号: 97, 页码: 88-97
作者:
Huo, Hui Jun
;
Chen, Shan Nan
;
Li, Li
;
Laghari, Zubair Ahmed
;
Li, Nan
  |  
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2019/07/01
IL-22
IL-22BP
Hepcidin
LEAP-2
Mandarin fish