中国科学院机构知识库网格
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Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 318
作者:
Wu, Li-ren
;
Peng, Qian-Yu
;
Li, Xue-Jian
;
Guo, Mei-Ying
;
He, Jia-Qi
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/11/10
Lung dysbiosis
Th1/Th2 balance
Antibiotic
GSK-3 ss
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
A zinc-modified
Anemarrhena asphodeloides
polysaccharide complex enhances immune activity
via
the NF-?B and MAPK signaling pathways
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 249, 页码: 12
作者:
Zhang, Shaojie
;
Zhang, Qian
;
Li, Chong
;
Xing, Na
;
Zhou, Pengfei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Anemarrhena asphodeloides Bunge
Zinc modification
Immunoregulatory activity
Zebrafish
NF-kappa B signaling pathway
MAPKs signaling pathway
HIF-1 alpha inhibition in macrophages preserves acute liver failure by reducing IL-1 beta production
期刊论文
OAI收割
FASEB JOURNAL, 2023, 卷号: 37, 期号: 9, 页码: 12
作者:
Kong, Xiangrong
;
Liu, Wei
;
Zhang, Xinwen
;
Zhou, Chendong
;
Sun, Xinyu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
acute liver failure
cell death
HIF-1 alpha inhibitor
interleukin-1 beta
macrophage
B-seco Limonoids with anti-inflammatory activity from Tetradium fraxinifolium (Hook.) TGHartley
期刊论文
OAI收割
FITOTERAPIA, 2023, 卷号: 169, 页码: 6
作者:
Jiang, Yu-Xia
;
Yao, Jia-Ying
;
Qin, Nan
;
Tan, Jun-Jie
;
Han, Feng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Tetradium fraxinifolium
Rutaceae
seco limonoids
Anti-inflammation
RAW264
7 cells
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 8, 页码: 3414-3424
作者:
Ji, Kailong
;
Liu, Wei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
Phychetins
Phyllanthus franchetianus
Structural elucidation
Total synthesis
Liver injury protection
Anti-inflammation
Acid-switchable nanoparticles induce self-adaptive aggregation for enhancing antitumor immunity of natural killer cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 7, 页码: 3093-3105
作者:
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Nanoparticle
Aggregation
Drug retention
Natural killer cells
Cancer immunotherapy
Acid-switchable
Galunisertib
IL-15
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:
Shi, Huanyu
;
Tang, Haotian
;
Li, Yan
;
Chen, Danqi
;
Liu, Tongchao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Cancer immunotherapy
SAR study
HPK1 inhibitors
Quinazoline-2
5-diamine
IL-2 production
Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 80, 页码: 117177
作者:
Yu, Yuanyuan
;
Yuan, Wenlong
;
Yuan, Jiaqi
;
Wei, Wenhui
;
He, Qian
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Osteoarthritis
Oleanolic acid derivatives
Anti-inflammatory
IL-1? inhibition
Antiosteoclastic activity