中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
昆明动物研究所 [2]
西双版纳热带植物园 [1]
数学与系统科学研究院 [1]
心理研究所 [1]
上海营养与健康研究所 [1]
更多
采集方式
OAI收割 [18]
内容类型
期刊论文 [18]
发表日期
2025 [2]
2024 [2]
2023 [1]
2021 [4]
2020 [1]
2019 [2]
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学科主题
Biotechnol... [1]
Research &... [1]
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浏览/检索结果:
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Discovery of novel Bis-amide analogue ST12 for the treatment of inflammatory bowel diseases (IBD) by inhibiting NLRP3 inflammasome activation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 159, 页码: 14
作者:
Sun, Zhiqiang
;
Zang, Qinru
;
Xu, Chenglong
;
Zhang, Xuewen
;
Kang, Zhenghui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
Anti-inflammatory agents
Nitric oxide (NO)
NLRP3 inflammasome
Inflammatory bowel diseases (IBD)
Oral FPR2/ALX modulators tune myeloid cell activity to ameliorate mucosal inflammation in inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Yang, Wen-sheng
;
Liu, Qing
;
Li, Yang
;
Li, Guan-yi
;
Lin, Shi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/24
IBD
FPR2/ALX
Quin-C1
Quin-C7
neutrophils
macrophages
A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:
Huang, Yuqing
;
Ning, Yi
;
Chen, Zhiwei
;
Song, Peiran
;
Tang, Haotian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/31
IRAK4 inhibitor
peritonitis
inflammatory bowel disease (IBD)
macrophage
Gut-brain axis interacts with immunomodulation in inflammatory bowel disease
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 219, 页码: 8
作者:
Ye, Xianglu
;
Zhang, Miao
;
Zhang, Ning
;
Wei, Hai
;
Wang, Bing
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2024/02/27
IBD
Gut-brain axis
Immunomodulation
Receptors
Lymphocytes
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade
期刊论文
OAI收割
EMBO JOURNAL, 2021, 页码: 16
作者:
Wang, Xu
;
Ni, Jiahui
;
You, Yan
;
Feng, Guize
;
Zhang, Sulin
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/12/16
E-cadherin
IBD
intestinal barrier function
LPS release
SNX10
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:
Li, Bo
;
Li, Heng
;
Zhu, Zhengdan
;
Xiang, Caigui
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
Anti-inflammatory activity
TNF alpha
ER beta
IBD Arylisoquinolones
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/11/24
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
Markov Jump Processes in Estimating Sharing of Identity by Descent
期刊论文
OAI收割
ACTA MATHEMATICAE APPLICATAE SINICA-ENGLISH SERIES, 2021, 卷号: 37, 期号: 1, 页码: 183-191
作者:
Chen, Xian
;
Guo, Wei
;
Ni, Xu-min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/04/26
IBD sharing
structured coalescent theory
Markov jump process
Kolmogorov backward equation
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way
期刊论文
OAI收割
FASEB JOURNAL, 2020, 页码: 16
作者:
Wu, Yanwei
;
Wu, Bing
;
Zhang, Zongwang
;
Lu, Huimin
;
Fan, Chen
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
IBD
M1
M2
ulcerative colitis