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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
上海营养与健康研究所 [6]
心理研究所 [3]
昆明植物研究所 [3]
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上海生物化学与细胞生... [3]
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OAI收割 [47]
内容类型
期刊论文 [46]
会议论文 [1]
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2025 [3]
2024 [2]
2023 [2]
2022 [5]
2021 [9]
2020 [3]
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Discovery of novel Bis-amide analogue ST12 for the treatment of inflammatory bowel diseases (IBD) by inhibiting NLRP3 inflammasome activation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 159, 页码: 14
作者:
Sun, Zhiqiang
;
Zang, Qinru
;
Xu, Chenglong
;
Zhang, Xuewen
;
Kang, Zhenghui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
Anti-inflammatory agents
Nitric oxide (NO)
NLRP3 inflammasome
Inflammatory bowel diseases (IBD)
Dehydrotrametenolic acid methyl ester, a triterpenoid of
Poria cocos
, alleviates non-alcoholic steatohepatitis by suppressing NLRP3 inflammasome activation via targeting Caspase-1 in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 17
作者:
Xia, Ling-yan
;
Yu, Nai-rong
;
Huang, Su-ling
;
Qu, Hui
;
Qin, Li
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
non-alcoholic steatohepatitis
dehydrotrametenolic acid methyl ester
NLRP3 inflammasome
caspase-1
macrophage-hepatocyte/HSC crosstalk
Discovery of novel biaryl urea derivatives against IL-1/3 release with low toxicity based on NEK7 inhibitor
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 12
作者:
Wang, Leibo
;
Zhu, Kehan
;
Tian, Ziyang
;
Wang, Haoyu
;
Jia, Yulei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/01/14
NLRP3 inflammasome
NEK7
NLRP3-NEK7
Inhibitors
Xuanbai Chengqi Decoction alleviates acute lung injury by inhibiting NLRP3 inflammasome
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319, 页码: 13
作者:
Wang, Shun
;
Lin, Feifei
;
Zhang, Chengxi
;
Gao, Dan
;
Qi, Zhuocao
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/12/08
Xuanbai Chengqi Decoction
Acute lung injury
NLRP3 inflammasome
Pyroptosis
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium
Forsythia suspensa
(Thunb.) Vahl extract ameliorates ulcerative colitis via inhibiting NLRP3 inflammasome activation through the TLR4/MyD88/NF-κB pathway
期刊论文
OAI收割
IMMUNITY INFLAMMATION AND DISEASE, 2023, 卷号: 11, 期号: 11, 页码: 14
作者:
Tong, Xiao
;
Chen, Li
;
He, Shijun
;
Liu, Shuangshuang
;
Yao, Jiaying
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/12/19
macrophages
NLRP3 inflammasome
phillygenin
ulcerative colitis
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 2, 页码: 434
作者:
Chen Jiali
;
Feng Zheling
;
Zhou Fei
;
Lou Ruohan
;
Peng Cheng
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/05/22
14-deoxygarcinol
adipose tissue inflammation
insulin resistance
interleukin-1β
NLRP3 inflammasome
Sirtuin 2
Chemotherapy-induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022, 页码: 16
作者:
Liu, Peng
;
Ye, Lichun
;
Ren, Yongshen
;
Zhao, Guodun
;
Zhang, Yun
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2023/04/10
aescin
GBP5
NLRP3 inflammasome
phlebitis
vinorelbine
Disruption of C/EBP beta-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 卷号: 20, 期号: 1, 页码: 19
作者:
Wu, Dan
;
Zhang, Yanqiong
;
Zhao, Chunhui
;
Li, Qiuyue
;
Zhang, Junhong
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2023/04/10
C/EBP beta-Clec7a axis
Neuroinflammation
Neuropathic Pain
NLRP3 Inflammasome-mediated Pyroptosis
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-kappa B/Sirtuin 2-NLRP3-mediated adipose tissue remodeling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Chen, Jia-li
;
Feng, Zhe-ling
;
Zhou, Fei
;
Lou, Ruo-han
;
Peng, Cheng
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/09/30
14-deoxygarcinol
adipose tissue inflammation
insulin resistance
interleukin-1 beta
NLRP3 inflammasome
Sirtuin 2