中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
金属研究所 [7]
上海神经科学研究所 [3]
心理研究所 [2]
武汉物理与数学研究所 [1]
昆明动物研究所 [1]
更多
采集方式
OAI收割 [29]
内容类型
期刊论文 [29]
发表日期
2025 [3]
2024 [1]
2022 [1]
2021 [1]
2018 [1]
2017 [1]
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学科主题
Neuroscien... [3]
Biochemist... [2]
健康心理学 [1]
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浏览/检索结果:
共29条,第1-10条
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Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Li, Kun
;
Zeng, Yue
;
Xiong, Yi-da
;
Wu, Hao-chen
;
Fang, Sui
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
drug-target affinity prediction
virtual screening
contrastive learning
graph neural network
N
-methyl-
D
-aspartate (NMDA) receptors
GluN3A subunit.
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8
作者:
Wang, Shi-hang
;
Zeng, Yue
;
Yang, Hao
;
Tian, Si-yuan
;
Zhou, Yong-qi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/25
N
-methyl-
D
-aspartate receptors
GluN1/GluN3A
ligand-based virtual screening
scaffold hopping
deep learning
GeminiMol
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Design, Synthesis and Bioactivity of NYX-2925
L
-Proline Derivatives as
N
-Methyl-D-aspartate (NMDA) Receptor Partial Agonists
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 4, 页码: 1247-1263
作者:
Wu Youjin
;
Jin Zhengsheng
;
Liu Yongjia
;
Huang Wenqian
;
Zhao Guilong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/08/22
N-methyl-D-aspartate (NMDA) receptor
partial agonist
NYX-2925
synthesis
bioactivity
Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 13
作者:
Zeng, Yue
;
Zheng, Yueming
;
Zhang, Tongtong
;
Ye, Fei
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/08/16
N-methyl-D-aspartate (NMDA) receptors
GluN3 subunits
WZB117
allosteric modulator
ion channels
drug discovery
Comprehensive B-Cell Immune Repertoire Analysis of Anti-NMDAR Encephalitis and Anti-LGI1 Encephalitis
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12, 页码: 12
作者:
Feng, Jingjing
;
Fan, Siyuan
;
Sun, Yinwei
;
Ren, Haitao
;
Guan, Hongzhi
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/12
anti-N-methyl-D-aspartate receptor encephalitis
anti-leucine-rich glioma-inactivated 1 encephalitis
B-cell immune repertoire
common clones
adaptive immune responses
GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1
期刊论文
OAI收割
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:
Zhou, Dongsheng
;
Lv, Dan
;
Wang, Zhen
;
Zhang, Yanhua
;
Chen, Zhongming
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
GLYX-13
disrupted-in-schizophrenia 1
N-methyl-D-aspartate receptor
N-methyl D-aspartate receptor subtype 2B
schizophrenia
Incorporation of Dihydroartemisinin into Memantine Through a Propriate Spacer to Make Hybrid with Enhanced Effects to Protect PC12 Cells from Corticosterone-caused Impairments
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 4, 页码: 611-622
作者:
Zhang Lei
;
Zhou Fan
;
Zhang Laitao
;
Peng Lizhi
;
Guo Cuiping
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Artemisinin
Memantine
Neuroprotection
N-Methyl-D-aspartate(NMDA) receptor
Depression
NMDA RECEPTOR ANTAGONISM BY REPETITIVE MK801 ADMINISTRATION INDUCES SCHIZOPHRENIA-LIKE STRUCTURAL CHANGES IN THE RAT BRAIN AS REVEALED BY VOXEL-BASED MORPHOMETRY AND DIFFUSION TENSOR IMAGING
期刊论文
OAI收割
NEUROSCIENCE, 2016, 卷号: 322, 页码: 221-233
作者:
Wu, H.
;
Wang, X.
;
Gao, Y.
;
Lin, F.
;
Song, T.
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2016/05/03
N-methyl-D-aspartate receptor
schizophrenia
magnetic resonance imaging
rat
brain
Brain cell apoptosis and enhancement of nervous excitability in pregnant rats with high plasma levels of homocysteine
期刊论文
OAI收割
NEURAL REGENERATION RESEARCH, 2012, 卷号: 7, 期号: 28, 页码: 2199-2205
作者:
Wang Jun
;
Ge Jing
;
Yang Liu
;
Zhang Haiyan
;
Li Xuli
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/02/26
NMDA RECEPTOR
PREECLAMPSIA
HYPERHOMOCYSTEINEMIA
HYPERTENSION
PATHOPHYSIOLOGY
MILD
JUNCTIONS
STRESS
DEATH
hyperhomocysteinemia
homocysteine
preeclampsia
frontal cortex
N-methyl-D-aspartate receptor
nerve excitability
cell apoptosis
pregnancy
brain
neural regeneration