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浏览/检索结果: 共81条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 New advances in small molecule drugs targeting NMDA receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 19 作者:  Zeng, Yue;  Qu, Zhi-yan;  Zhu, Qian-wen;  Wang, Hai-ying;  Zhou, Yu   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/12/04 N-methyl-D-aspartate (NMDA) receptor  small-molecule modulators  depression  CNS disorders  channel blocker  allosteric modulator   Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10 作者:  Yang, Yurong;  Xiao, Fuling;  Zuo, Jianping;  Yang, Li;  Hu, Youhong   |  收藏  |  浏览/下载：74/0  |  提交时间：2025/08/20 HBV  Capsid assembly modulators  Structural optimization  Oxidative metabolism   Structural Properties, Pathophysiological Relevance and Synthetic Modulators of TRPC Channels 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2025, 页码: 37 作者:  Qiao, Xue;  Ren, Chunlin;  Wang, Wumei;  Wang, Xiaofen;  Li, Guo-Bo   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/12/04 cryo-electron microscopy structure  modulators  physiological  TRP  TRPC   An updated patent review of TEAD modulators (2022-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 27 作者:  Xu, Dounan;  Zhong, Jiahuan;  Zeng, Yuhan;  Zhang, Xianhui;  Wang, Chengyu   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/12/04 Hippo signaling pathway  transcriptional enhanced associated domain (TEAD)  modulators  anti-cancer drugs  degraders  combination therapy   Discovery of novel small molecules targeting hepatitis B virus core protein from marine natural products with HiBiT-based high-throughput screening 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4914-4933 作者:  Huang, Chao;  Jin, Yang;  Fu, Panpan;  Hu, Kongying;  Wang, Mengxue   |  收藏  |  浏览/下载：52/0  |  提交时间：2025/01/06 Anti-HBV  HBV core protein  Core protein assembly modulators  Marine natural products  HiBiT  Lead compound  Naamidine J derivative  Bioactivity-driven synthesis   Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators 期刊论文  OAI收割 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868 作者:  Wang, Yun-Qi;  Guan, Zi-Yue;  Gao, Zhao-Bing;  Zheng, Yue-Ming   |  收藏  |  浏览/下载：79/0  |  提交时间：2024/04/09 TRPM7  ion channel  physiological function  disease  small molecule modulators   A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8 作者:  Chen, Wuhong;  Gong, Ying;  Long, Guozhang;  Wang, Xinran;  Yang, Yurong   |  收藏  |  浏览/下载：60/0  |  提交时间：2023/10/17 HBV  Capsid assembly modulators  Prodrug  Hepatitis B surface antigen   Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088 作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan   |  收藏  |  浏览/下载：66/0  |  提交时间：2024/05/09 euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS   Euphpepluone S, a new lathyrane diterpenoid with anti-inflammatory activity from Euphorbia peplus L. 期刊论文  OAI收割 PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 61-66 作者:  Guan,Shi-Peng;  Yang,Ying;  Sun,Mao;  Cai,Min;  Pu,Xue-Xue   |  收藏  |  浏览/下载：67/0  |  提交时间：2024/07/22 Diterpenoids  Lathyrane  Anti-inflammatory activity  DP4+  Euphorbia peplus  Dexamethasone  CASBANE DITERPENOIDS  JATROPHANE DITERPENOIDS  MODULATORS  ROOTS   Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya   |  收藏  |  浏览/下载：138/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators