机构

• 上海药物研究所 [7]
• 昆明动物研究所 [1]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2025 [2]
• 2022 [1]
• 2012 [1]
• 2006 [1]
• 2002 [1]
• 2000 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13 作者:  Li, Kun;  Zeng, Yue;  Xiong, Yi-da;  Wu, Hao-chen;  Fang, Sui   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 drug-target affinity prediction  virtual screening  contrastive learning  graph neural network  N-methyl-D-aspartate (NMDA) receptors  GluN3A subunit.   Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8 作者:  Wang, Shi-hang;  Zeng, Yue;  Yang, Hao;  Tian, Si-yuan;  Zhou, Yong-qi   |  收藏  |  浏览/下载：11/0  |  提交时间：2025/07/25 N-methyl-D-aspartate receptors  GluN1/GluN3A  ligand-based virtual screening  scaffold hopping  deep learning  GeminiMol   Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 13 作者:  Zeng, Yue;  Zheng, Yueming;  Zhang, Tongtong;  Ye, Fei;  Zhan, Li   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/08/16 N-methyl-D-aspartate (NMDA) receptors  GluN3 subunits  WZB117  allosteric modulator  ion channels  drug discovery   Novel glycine-dependent inactivation of NMDA receptors in cultured hippocampal neurons 期刊论文  OAI收割 NEUROSCIENCE BULLETIN, 2012, 卷号: 28, 期号: 5, 页码: 550 作者:  Zhang YunFeng;  Li Xia;  Peng LiangLiang;  Wang GuoHua;  Ke KaiFu   |  收藏  |  浏览/下载：57/0  |  提交时间：2020/12/24 MOLECULAR DETERMINANTS  INTERNALIZATION  MODULATION  CHANNELS  SUBUNIT  glycine  N-methyl-D-aspartate receptors  calcium imaging  NMDA-NR1 subunit  hippocampal neurons  inactivation   NR2B-containing N-methyl-D-aspartate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo 期刊论文  OAI收割 NEUROREPORT, 2006, 卷号: 17, 期号: 12, 页码: 1343-1346 作者:  Wang MN;  Yang Y;  Dong ZF;  Cao J[*];  Xu L[*] 收藏  |  浏览/下载：37/0  |  提交时间：2017/02/22 adult  acute stress  NR2B-containing N-methyl-D-aspartate subtype glutamate receptors  anesthetized rats  Ro25-6981  long-term potentiation  long-term depression   Spermidine antagonizes the inhibitory effect of huperzine A on [H-3]dizocilpine (MK-801) binding in synaptic membrane of rat cerebral cortex 期刊论文  OAI收割 NEUROSCIENCE LETTERS, 2002, 卷号: 319, 期号: 2, 页码: 107-110 作者:  Zhang, YH;  Zhao, XY;  Chen, XQ;  Wang, Y;  Yang, HH   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 huperzine A  cholinesterase inhibitor  Alzheimer's disease  [H-3]dizocilpine (MK-801) binding  N-methyl-D-aspartate receptors  polyamine   Dopamine-glutamate interaction in rat striatal slices: changes of CCDPK II, PKA, and LDH activity by receptor-mediated mechanisms 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2000, 卷号: 21, 期号: 2, 页码: 145-150 作者:  Tang, FM;  Sun, YF;  Wang, R;  Ding, YM;  Zhang, GY   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 dopamine  glutamates  dopamine receptors  N-methyl-D-aspartate receptors  corpus striatum  Ca2+-calmodulin dependent protein kinase  cyclic AMP-dependent protein kinases  lactate dehydrogenase   Modulation of NMDA receptor by huperzine A in rat cerebral cortex 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 1999, 卷号: 20, 期号: 1, 页码: 31-35 作者:  Wang, XD;  Zhang, JM;  Yang, HH;  Hu, GY   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 huperzine A  cholinesterase inhibitors  N-methyl-D-aspartate receptors  sodium glutamate  dizocilpine maleate  hippocampus  pyramidal cells  cerebral cortex  patch-clamp techniques  radioligand assay