中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [63]
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Discovery of (±)-Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 9
作者:
Meng, Ling-Hong
;
Awakawa, Takayoshi
;
Li, Xiao-Ming
;
Quan, Zhiyang
;
Yang, Sui-Qun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/29
Fungal natural products
Indole alkaloid
biosynthesis
Heterologous expression
Cytochrome P450 oxidase
Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/05/07
artemisinin
Asteraceae sesquiterpene lactone
cytochrome P450 monooxygenases
amorpha-4
11-diene oxidase
germacrene A oxidase
molecular evolution
loss-of-function event
Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design
期刊论文
OAI收割
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3
作者:
Gao, Qilin
;
Ma, Bingbing
;
Wang, Qianwen
;
Zhang, Hao
;
Fushinobu, Shinya
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/27
P450
testosterone
androstenedione
crystal structure
rational design
A Mushroom P450-Monooxygenase Enables Regioand Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 49
作者:
Yang,Yan-Long
;
Zhou,Man
;
Yang,Lin
;
Gressler,Markus
;
Rassbach,Johannes
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/07/10
Biocatalysis
Biosynthesis
Cytochrome P450
Epoxycyclohexenone
Natural Products
OPPOSITE FACIAL SPECIFICITY
NATURAL-PRODUCTS
STREPTOMYCES LL-C10037
BIOSYNTHESIS
EPOXYQUINONE
CYTOCHROME-P450
FERMENTATION
PANEPOXYDONE
EPOXIDATION
INHIBITION
A Novel CYP4 Gene Identified in the Polychaete Sternaspis scutata and Its Transcriptional Levels along the Coasts of the Liaodong Peninsula
期刊论文
OAI收割
WATER, 2022, 卷号: 14, 期号: 21, 页码: 12
作者:
Yu, Zhenglin
;
Qi, Aimin
;
Wang, Lili
;
Shan, Encui
;
Li, Dongmei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/08/17
cytochrome P450
polychaetes
Sternaspis sculata
transcriptional response
PAHs
field study
A Novel CYP4 Gene Identified in the Polychaete Sternaspis scutata and Its Transcriptional Levels along the Coasts of the Liaodong Peninsula
期刊论文
OAI收割
WATER, 2022, 卷号: 14, 期号: 21, 页码: 12
作者:
Yu, Zhenglin
;
Qi, Aimin
;
Wang, Lili
;
Shan, Encui
;
Li, Dongmei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/15
cytochrome P450
polychaetes
Sternaspis sculata
transcriptional response
PAHs
field study
Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
An aggregation-induced emission fluorescence probe for evaluating the effect of CYP450 changes under tumor chemotherapy
期刊论文
OAI收割
TALANTA, 2022, 卷号: 239, 页码: 9
作者:
Lu, Pengpeng
;
Huang, Yan
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/07/04
Cytochrome P450
Fluorescence imaging
Chemotherapy
Liver cancer
An aggregation-induced emission fluorescence probe for evaluating the effect of CYP450 changes under tumor chemotherapy
期刊论文
OAI收割
TALANTA, 2022, 卷号: 239, 页码: 9
作者:
Lu, Pengpeng
;
Huang, Yan
;
Zhang, Caiyun
;
Fu, Lili
;
Wang, Xiaoyan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/12/07
Cytochrome P450
Fluorescence imaging
Chemotherapy
Liver cancer