中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共209条,第1-10条 帮助

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Impact of electrostatic distribution in CYP3A4 on the regioselectivity of triazolam metabolism and regulation of its metabolic rate by the iron spin states: Insights from MD simulations and QM calculations 期刊论文  OAI收割
JOURNAL OF INORGANIC BIOCHEMISTRY, 2026, 卷号: 276, 页码: 12
作者:  
Zhao, Yan;  Ma, Xinyu;  Zheng, Qingchuan
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Mechanism of hydroxamic acid group metabolism to carboxylic acid: Oxidation versus hydrolysis 期刊论文  OAI收割
DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 10, 页码: 11
作者:  
Huang, Xiyue;  Zhou, Lei;  Chen, Huixian;  Sun, Xiaowei;  Cao, Mengyi
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Pharmacokinetics, mass balance, and metabolism of [14C]SAF-189s, a potent anaplastic lymphoma kinase/c-ROS proto-oncogene 1 inhibitor in humans: Metabolism potentially affected by interaction of cytochrome P450 enzymes and intestinal microbiota 期刊论文  OAI收割
DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 9, 页码: 14
作者:  
Yang, Ming;  Diao, Lei;  Yan, Shu
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Discovery of (±)-Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 9
作者:  
Meng, Ling-Hong;  Awakawa, Takayoshi;  Li, Xiao-Ming;  Quan, Zhiyang;  Yang, Sui-Qun
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Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis 期刊论文  OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:  
Chen, Fang-Yan;  Mu, Qiu-Yan;  Xu, Bing-Yi;  Lei, Yu-Chen;  Liu, Hui-Ying
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:  
Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao
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Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design 期刊论文  OAI收割
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3
作者:  
Gao, Qilin;  Ma, Bingbing;  Wang, Qianwen;  Zhang, Hao;  Fushinobu, Shinya
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A Mushroom P450-Monooxygenase Enables Regioand Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 49
作者:  
Yang,Yan-Long;  Zhou,Man;  Yang,Lin;  Gressler,Markus;  Rassbach,Johannes
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A Novel CYP4 Gene Identified in the Polychaete Sternaspis scutata and Its Transcriptional Levels along the Coasts of the Liaodong Peninsula 期刊论文  OAI收割
WATER, 2022, 卷号: 14, 期号: 21, 页码: 12
作者:  
Yu, Zhenglin;  Qi, Aimin;  Wang, Lili;  Shan, Encui;  Li, Dongmei
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A Novel CYP4 Gene Identified in the Polychaete Sternaspis scutata and Its Transcriptional Levels along the Coasts of the Liaodong Peninsula 期刊论文  OAI收割
WATER, 2022, 卷号: 14, 期号: 21, 页码: 12
作者:  
Yu, Zhenglin;  Qi, Aimin;  Wang, Lili;  Shan, Encui;  Li, Dongmei
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