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Impact of electrostatic distribution in CYP3A4 on the regioselectivity of triazolam metabolism and regulation of its metabolic rate by the iron spin states: Insights from MD simulations and QM calculations
期刊论文
OAI收割
JOURNAL OF INORGANIC BIOCHEMISTRY, 2026, 卷号: 276, 页码: 12
作者:
Zhao, Yan
;
Ma, Xinyu
;
Zheng, Qingchuan
  |  
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Mechanism of hydroxamic acid group metabolism to carboxylic acid: Oxidation versus hydrolysis
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 10, 页码: 11
作者:
Huang, Xiyue
;
Zhou, Lei
;
Chen, Huixian
;
Sun, Xiaowei
;
Cao, Mengyi
  |  
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Pharmacokinetics, mass balance, and metabolism of [
14
C]SAF-189s, a potent anaplastic lymphoma kinase/c-ROS proto-oncogene 1 inhibitor in humans: Metabolism potentially affected by interaction of cytochrome P450 enzymes and intestinal microbiota
期刊论文
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DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 9, 页码: 14
作者:
Yang, Ming
;
Diao, Lei
;
Yan, Shu
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Discovery of (±)-Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase
期刊论文
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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 9
作者:
Meng, Ling-Hong
;
Awakawa, Takayoshi
;
Li, Xiao-Ming
;
Quan, Zhiyang
;
Yang, Sui-Qun
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Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
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FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
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Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design
期刊论文
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APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3
作者:
Gao, Qilin
;
Ma, Bingbing
;
Wang, Qianwen
;
Zhang, Hao
;
Fushinobu, Shinya
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A Mushroom P450-Monooxygenase Enables Regioand Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones
期刊论文
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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 49
作者:
Yang,Yan-Long
;
Zhou,Man
;
Yang,Lin
;
Gressler,Markus
;
Rassbach,Johannes
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A Novel CYP4 Gene Identified in the Polychaete Sternaspis scutata and Its Transcriptional Levels along the Coasts of the Liaodong Peninsula
期刊论文
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WATER, 2022, 卷号: 14, 期号: 21, 页码: 12
作者:
Yu, Zhenglin
;
Qi, Aimin
;
Wang, Lili
;
Shan, Encui
;
Li, Dongmei
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  |  
A Novel CYP4 Gene Identified in the Polychaete Sternaspis scutata and Its Transcriptional Levels along the Coasts of the Liaodong Peninsula
期刊论文
OAI收割
WATER, 2022, 卷号: 14, 期号: 21, 页码: 12
作者:
Yu, Zhenglin
;
Qi, Aimin
;
Wang, Lili
;
Shan, Encui
;
Li, Dongmei
  |  
收藏
  |