中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共29条,第1-10条 帮助

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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:  
Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao
  |  收藏  |  浏览/下载:10/0  |  提交时间:2023/12/08
Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221
作者:  
He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon
  |  收藏  |  浏览/下载:15/0  |  提交时间:2023/05/22
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:  
He, Yi-fei;  Liu, Yin;  Yu, Jing-hua;  Cheng, Huan;  Odilov, Abdullajon
  |  收藏  |  浏览/下载:31/0  |  提交时间:2022/08/16
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  
Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
  |  收藏  |  浏览/下载:48/0  |  提交时间:2021/08/17
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:  
Xu, Ye;  Zhang, Yi-fan;  Chen, Xiao-yan;  Zhong, Da-fang
  |  收藏  |  浏览/下载:25/0  |  提交时间:2019/01/08
Pharmacokinetic Drug Interactions of Apatinib With Rifampin and Itraconazole 期刊论文  OAI收割
JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 卷号: 58, 期号: 3, 页码: 347-356
作者:  
Liu, Xiaoyun;  Zhang, Yifan;  Chen, Qian;  Zhan, Yan;  Wang, Quanren
  |  收藏  |  浏览/下载:49/0  |  提交时间:2019/01/08
cyp3a4inducerandinhibitorstronglyaffectthepharmacokineticsoftriptolideanditsderivativeinrats 期刊论文  OAI收割
actapharmacologicasinica, 2018, 卷号: 039, 期号: 008, 页码: 1386
作者:  
Xu Ye;  Zhang Yifan;  Chen Xiaoyan;  Zhong Dafang
  |  收藏  |  浏览/下载:10/0  |  提交时间:2020/07/01
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis 期刊论文  OAI收割
FITOTERAPIA, 2017, 卷号: 119, 页码: 26-31
作者:  
Zhao, Jin;  Sun, Tao;  Wu, Jing-Jing;  Cao, Yun-Feng;  Fang, Zhong-Ze
  |  收藏  |  浏览/下载:38/0  |  提交时间:2017/10/29
Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice 期刊论文  OAI收割
toxicology in vitro, 2015, 卷号: 29, 期号: 7, 页码: 1569-1576
作者:  
He, Wei;  Wu, Jing-Jing;  Ning, Jing;  Hou, Jie;  Xin, Hong
收藏  |  浏览/下载:32/0  |  提交时间:2015/11/17
A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4 期刊论文  OAI收割
international journal of molecular sciences, 2015, 卷号: 16, 期号: 7, 页码: 14677-14694
作者:  
Dai, Zi-Ru;  Ai, Chun-Zhi;  Ge, Guang-Bo;  He, Yu-Qi;  Wu, Jing-Jing
收藏  |  浏览/下载:25/0  |  提交时间:2015/11/17