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	Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19 作者: Wang, Pingyuan; Zhu, Wen-Ting; Wang, Yajing; Song, Shan-Shan; Xi, Yong \| 收藏 \| 浏览/下载：70/0 \| 提交时间：2023/10/17 PARP1 inhibitor Synthetic lethality Drug resistance Anticancer Structure -activity relationship
	Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者: Cao, Guo-Zhen; Ma, Li-Ying; Zhang, Zong-Hui; Wang, Xiao-Lin; Hua, Jing-Han \| 收藏 \| 浏览/下载：47/0 \| 提交时间：2022/12/22 small-cell lung cancer H3 3 PARP1 PARP inhibitor darinaparsin combination treatment
	Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity 期刊论文 OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 714-727 作者: Chen, Hua-Dong; Chen, Chuan-Huizi; Wang, Yu-Ting; Guo, Ne; Tian, Yu-Nan \| 收藏 \| 浏览/下载：13/0 \| 提交时间：2024/03/21 PARP1 inhibitor PARP1-DNA binding PARP1-DNA trapping poly(ADP-ribose) polymerase activity cytotoxicity
	Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 389-403 作者: Chen, Xuxing; Huan, Xiajuan; Liu, Qiufeng; Wang, Yuqin; He, Qian \| 收藏 \| 浏览/下载：36/0 \| 提交时间：2019/01/08 PARP1/2 inhibitor Benzimidazole 4,5,6,7-Tetrahydrothienopyridine Co-crystal structure Isothermal Titration Calorimetry