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	Characterization of preclinical radio ADME properties of ARV-471 for predicting human PK using PBPK modeling 期刊论文 OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2025, 卷号: 15, 期号: 5, 页码: 15 作者: He, Yifei; Zhu, Chenggu; Lei, Peng; Yang, Chen; Zhang, Yifan \| 收藏 \| 浏览/下载：4/0 \| 提交时间：2025/08/20 PROTAC Vepdegestrant (ARV-471) Radiolabeling In vitro-in vivo extrapolation (IVIVE) Physiologically based pharmacokinetic (PBPK) model
	Effect of Enterohepatic Circulation on the Accumulation of Per- and Polyfluoroalkyl Substances: Evidence from Experimental and Computational Studies 期刊论文 OAI收割 ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 5, 页码: 3214-3224 作者: Cao, Huiming; Zhou, Zhen; Hu, Zhe; Wei, Cuiyun; Li, Jie \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2022/11/08 PERFLUOROOCTANE SULFONATE PFOS PHARMACOKINETIC PBPK MODEL PERFLUORINATED ALKYL ACIDS BOVINE SERUM-ALBUMIN PERFLUOROALKYL ACIDS MOLECULAR DOCKING BINDING-AFFINITY TANGXUN LAKE BILE-ACIDS ELIMINATION
	Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 11, 页码: 1359 作者: Li Guofu; Wang Kun; Chen Rui; Zhao Haoru; Yang Jin \| 收藏 \| 浏览/下载：33/0 \| 提交时间：2020/12/24 TISSUE DISTRIBUTION DRUG DISCOVERY INTRASUBJECT VARIABILITY PBPK SIMULATION P-GP ABSORPTION POPULATION PREDICTION BIOAVAILABILITY IDENTIFICATION bisoprolol whole-body physiologically based pharmacokinetic model drug absorption drug distribution renal function impairment