机构

• 上海药物研究所 [19]
• 金属研究所 [2]
• 昆明植物研究所 [2]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2024 [3]
• 2021 [2]
• 2018 [3]
• 2013 [5]
• 2012 [1]
• 2009 [3]
• 更多

学科主题

• Pharmacolo... [2]
• Behavioral... [1]
• Biotechnol... [1]
• Chemistry [1]
• Microbiolo... [1]
• Mycology [1]
• 更多

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13 作者:  Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/08/22 Receptor -interacting protein kinase 1  Histone deacetylases  Inhibitor  Molecular dynamics (MD) simulation  ADMET analysis   Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 16 作者:  An, Yuxiang;  Peng, Xia;  Wang, Tianchen;  Liu, Kaiyuan;  Feng, Dazhi   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/12/25 inhibitor  pharmacokinetic study  pyridazin-4-one  receptor-interacting protein kinase 1  selectivity   Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2024, 页码: 21 作者:  Lan, Yaohan;  Ji, Yinchun;  Peng, Xia;  Duan, Wenhu;  Geng, Meiyu   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/08/22 autoimmune disease  necroptosis inhibitor  pharmacokinetic profile  receptor interacting protein kinase 1 (RIPK1)  structural optimization   Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 219, 页码: 12 作者:  Rao, Danni;  Li, Heng;  Ren, Xuelian;  Sun, Yaoliang;  Wen, Cuiyun   |  收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17 Zeta-chain associated protein kinase 70 kDa (ZAP-70)  Covalent inhibitor  T cell  Autoimmune diseases   Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963 作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/04/02 Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN   Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562 作者:  Liu, Feifei   |  收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 Mitogen-activated protein kinases  Extracellular signal-regulated kinase  ERK inhibitor  ERK kinase  Cancer therapy  Drug resistance   Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86 作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin   |  收藏  |  浏览/下载：190/0  |  提交时间：2019/01/08 Heat shock protein 90 (Hsp90)  Tyrosine kinase ALK  Dual inhibitor  Drug resistance  Antiproliferative activity   targetingerkanachillesheelofthemapkpathwayincancertherapy 期刊论文  OAI收割 actapharmaceuticasinicab, 2018, 卷号: 8, 期号: 4, 页码: 552 作者:  Liu Feifei;  Yang Xiaotong;  Geng Meiyu;  Huang Min   |  收藏  |  浏览/下载：70/0  |  提交时间：2020/07/01 Mitogen-activated protein kinases  Extracellular signal-regu lated kinase  ERK inhibitor  ERK kinase  Cancer therapy  Drug resistance   Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1475-1483 作者:  Yu, Zhe;  Ma, Yu-chi;  Ai, Jing;  Chen, Dan-qi;  Zhao, Dong-mei   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 receptor tyrosine kinase  type I c-Met inhibitor  cancer  quantum chemistry  protein-ligand interaction  symmetry-adapted perturbation theory (SAPT)   Transcriptome-Wide Mapping of Pea Seed Ageing Reveals a Pivotal Role for Genes Related to Oxidative Stress and Programmed Cell Death 期刊论文  OAI收割 PLOS ONE, 2013, 卷号: 8, 期号: 10 作者:  Chen, Hongying;  Osuna, Daniel;  Colville, Louise;  Lorenzo, Oscar;  Graeber, Kai 收藏  |  浏览/下载：149/0  |  提交时间：2014/01/13 PROTEIN S-GLUTATHIONYLATION  SIGNAL-REGULATING KINASE-1  ARABIDOPSIS-THALIANA  BAX INHIBITOR-1  DIFFERENTIAL EXPRESSION  LIPID-PEROXIDATION  INDUCED APOPTOSIS  MESSENGER-RNA  NICOTIANA-BENTHAMIANA  MICROARRAY ANALYSIS