中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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理论物理研究所 [2]
上海生物化学与细胞生... [2]
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OAI收割 [9]
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期刊论文 [9]
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2010 [2]
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Physics [2]
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Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway
期刊论文
OAI收割
BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33
作者:
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收藏
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浏览/下载:65/0
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提交时间:2018/10/11
Huntington's Disease
Polyglutamine
Intravenous Immunoglobulin
Huntingtin Protein
PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin
期刊论文
OAI收割
FASEB JOURNAL, 2018, 卷号: 32, 期号: 6, 页码: 2923-2933
作者:
Yang, Hui
;
Yue, Hong-Wei
;
He, Wen-Tian
;
Hong, Jun-Ye
;
Jiang, Lei-Lei
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收藏
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浏览/下载:31/0
  |  
提交时间:2019/04/28
Protein-quality Control
Group-c Protein
Polyglutamine Disease
Alpha-synuclein
Neurodegenerative Diseases
Parkinsons-disease
Nuclear Inclusions
Nucleocytoplasmic Transport
Deubiquitinating Function
Cytoplasmic Inclusions
Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2016, 卷号: 17, 期号: 2, 页码: 270-282
作者:
Li, Chen
;
Chang, Catherine Ching Han
;
Nagel, Jeremy
;
Porebski, Benjamin T.
;
Hayashida, Morihiro
收藏
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浏览/下载:54/0
  |  
提交时间:2017/03/13
coiled-coil
prediction
oligomeric state
polyglutamine
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease
期刊论文
OAI收割
HUMAN MOLECULAR GENETICS, 2013, 卷号: 22, 期号: 18, 页码: 3641-3653
作者:
Wang, Fengli
;
Yang, Yeran
;
Lin, Xiwen
;
Wang, Jiu-Qiang
;
Wu, Yong-Sheng
收藏
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浏览/下载:51/0
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提交时间:2013/10/16
EMBRYONIC STEM-CELLS
ADULT HIPPOCAMPAL NEUROGENESIS
TRANSGENIC MOUSE MODEL
DNA METHYLATION
GENE-EXPRESSION
MUTANT HUNTINGTIN
NERVOUS-SYSTEM
POLYGLUTAMINE PATHOGENESIS
MITOCHONDRIAL DYSFUNCTION
MAMMALIAN DEVELOPMENT
Structural basis for recognition of the third SH3 domain of full-length R85 (R85FL)/ponsin by ataxin-7
期刊论文
OAI收割
FEBS LETTERS, 2013, 卷号: 587, 期号: 18, 页码: 2905-2911
作者:
Jiang, YJ
;
Zhou, CJ
;
Zhou, ZR
;
Wu, M
;
Hu, HY
收藏
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浏览/下载:45/0
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提交时间:2015/07/22
Ataxin-7
Proline-rich region
R85FL/ponsin
SH3 domain
Polyglutamine
Inclusion body
Concentration and Temperature Dependences of Polyglutamine Aggregation by Multiscale Coarse-Graining Molecular Dynamics Simulations
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2012, 卷号: 116, 期号: 34, 页码: 10135-10144
作者:
Ou-yang, ZC
;
Wang, YT
收藏
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浏览/下载:109/0
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提交时间:2014/04/25
FLUORESCENCE CORRELATION SPECTROSCOPY
AMYLOID-LIKE FIBRILS
HUNTINGTONS-DISEASE
NEURODEGENERATIVE DISEASES
IONIC LIQUIDS
MONOMERIC POLYGLUTAMINE
PROTEIN AGGREGATION
MUTANT HUNTINGTIN
PEPTIDES
MECHANISMS
Concentration and Temperature Dependences of Polyglutamine Aggregation by Multiscale Coarse-Graining Molecular Dynamics Simulations
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2012, 卷号: 116, 期号: 34, 页码: 10135
Deng, L
;
Wang, YT
;
Ou-yang, ZC
收藏
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浏览/下载:22/0
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提交时间:2013/09/17
FLUORESCENCE CORRELATION SPECTROSCOPY
AMYLOID-LIKE FIBRILS
HUNTINGTONS-DISEASE
NEURODEGENERATIVE DISEASES
IONIC LIQUIDS
MONOMERIC POLYGLUTAMINE
PROTEIN AGGREGATION
MUTANT HUNTINGTIN
PEPTIDES
MECHANISMS
Molecular Dynamics Simulations of Polyglutamine Aggregation Using Solvent-Free Multiscale Coarse-Grained Models
期刊论文
OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2010, 卷号: 114, 期号: 26, 页码: 8735-8743
作者:
Wang, Yanting
;
Voth, Gregory A.
;
Voth, GA , Univ Chicago, James Franck Inst, Dept Chem, Chicago, IL 60637 USA
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收藏
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浏览/下载:24/0
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提交时间:2012/08/02
Amyloid-like Fibrils
Ionic Liquids
Huntingtons-disease
Neurodegenerative Diseases
Monomeric Polyglutamine
Potential Functions
Lipid-bilayer
Peptides
Proteins
Kinetics