中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [600]
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共1766条,第1-10条
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Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-62
作者:
M Iijima
;
T Yoshimizu
;
T Shimazaki
;
K Tokugawa
;
K Fukumoto
  |  
收藏
  |  
浏览/下载:617/0
  |  
提交时间:2017/07/24
Arginine Vasopressin
V1b Receptor Antagonist
Depression
Anxiety
Hpa Axis
Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons1
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-34
作者:
Fang Qiu
;
Chun-Yu Qiu
;
Huilan Cai
;
Ting-Ting Liu
;
Zu-Wei Qu
  |  
收藏
  |  
浏览/下载:398/0
  |  
提交时间:2017/07/24
Oxytocin
Acid-sensing Ion Channel
Proton-gated Current
Vasopressin-1a Receptor
Dorsal Root Ganglion Neuron
Electrophysiology
Pain
Pharmacological characterizationof tachykinin tetrabranched derivatives
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-36
作者:
Chiara Ruzza
;
Anna Rizzi
;
Davide Malfacini
;
Maria Camilla Cerlesi
;
Federica Ferrari
  |  
收藏
  |  
浏览/下载:197/0
  |  
提交时间:2017/07/24
Tachykinins
Substance p
Pwt2-sp
Nk1 Receptor
Calcium Mobilization
Bioluminescence Resonance Energy Transfer
Guinea Pig Ileum
Rat Urinary Bladder
Nociceptive Behaviour Induced By Spinal Substance p
Mice
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
OAI收割
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
  |  
收藏
  |  
浏览/下载:244/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Targeting AhR suppresses hepatocyte ferroptosis in MASH by regulating the Pten/Akt/β catenin axis
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 232, 页码: 13
作者:
Ma, Chenhui
;
Han, Li
;
Zhao, Wenxuan
;
Chen, Feihong
;
Huang, Ruimin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/01
Metabolic dysfunction-associated steatohepati-
tis
Liver disease
Iron
Ferroptosis
Aryl hydrocarbon Receptor
Pten
beta-catenin
Drug discovery targeting thyroid hormone receptor f3 (THRf3) for the treatment of liver diseases and other medical indications
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 35-51
作者:
Wang, Kean
;
Chen, Feiyang
;
Wang, Jiang
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Thyroid hormone
Thyroid hormone /3 receptor
MASLD
MASH
THR/3 agonist
Weight Loss Blockbuster Development: A Role for Unimolecular Polypharmacology
期刊论文
OAI收割
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2025, 卷号: 65, 页码: 191-213
作者:
Zhou, Qingtong
;
Li, Guanyi
;
Hang, Kaini
;
Li, Jie
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
overweight
glucagon-like peptide-1 receptor
unimolecular
polypharmacology
tirzepatide
retatrutide
metabolic diseases
Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 51, 页码: 12
作者:
Xu, Jiuyin
;
Xu, Youwei
;
Hou, Li
;
He, Xinheng
;
Li, Yang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/02/28
prostaglandin receptor
DP2
lipid regulation
receptor activation
signal bias
Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:
Tang, Mingze
;
Zhou, Xuan
;
Shen, Qianqian
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/22
Receptor -interacting protein kinase 1
Histone deacetylases
Inhibitor
Molecular dynamics (MD) simulation
ADMET analysis