中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
上海神经科学研究所 [5]
上海生物化学与细胞生... [2]
生物物理研究所 [1]
中国科学院大学 [1]
合肥物质科学研究院 [1]
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采集方式
OAI收割 [17]
iSwitch采集 [1]
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期刊论文 [15]
学位论文 [2]
会议论文 [1]
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2023 [1]
2018 [1]
2016 [1]
2015 [1]
2013 [3]
2012 [2]
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Cell Biolo... [3]
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A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942
作者:
Jiang, Hao
;
Zu, Shijia
;
Lu, Yu
;
Sun, Zhongya
;
Adeerjiang, Akejiang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/03/27
Small GTPases
Crystal structures of RhoA
Dynamics of switch II
Molecular dynamics simulations
Allosteric pocket
Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway
期刊论文
OAI收割
Journal of Experimental & Clinical Cancer Research, 2018, 卷号: 37
作者:
Chen,Xueran
;
Zhang,Shangrong
;
Wang,Zhen
;
Wang,Fengsong
;
Cao,Xinwang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/10/21
Supervillin
RhoA/ROCK
ERK/P38
EMT
HCC
Noncanonical myo9b-rhogap accelerates rhoa gtp hydrolysis by a dual-arginine-finger mechanism
期刊论文
iSwitch采集
Journal of molecular biology, 2016, 卷号: 428, 期号: 15, 页码: 3043-3057
作者:
Yi, Fengshuang
;
Kong, Ruirui
;
Ren, Jinqi
;
Zhu, Li
;
Lou, Jizhong
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/05/09
Rho gtpases
Gtpase-activating proteins
Rhogap domain
Myo9b
Rhoa
Development of Second-Generation Small-Molecule RhoA Inhibitors with Enhanced Water Solubility, Tissue Potency, and Significant in vivo Efficacy
期刊论文
OAI收割
CHEMMEDCHEM, 2015, 卷号: 10, 期号: 1, 页码: 193-206
作者:
Ma, Sheng
;
Deng, Jing
;
Li, Baoli
;
Li, Xiujiang
;
Yan, Zhaowei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
cardiovascular agents
RhoA inhibitors
subarachnoid hemorrhage
water solubility
vasorelaxation
Down-regulation of dorsal striatal RhoA activity and impairment of working memory in middle-aged rats
期刊论文
OAI收割
NEUROBIOLOGY OF LEARNING AND MEMORY, 2013, 卷号: 103, 页码: 3-10
作者:
Kang, Shuo
;
Ling, Qing-lan
;
Liu, Wen-tao
;
Lu, Bin
;
Liu, Yao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
RhoA
Neuroplasticity
Aging
Working memory
Dorsal Striatum
The small GTPase RhoA, but not Rac1, is essential for conditioned aversive memory formation through regulation of actin rearrangements in rat dorsal hippocampus
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 6, 页码: 811-818
作者:
Wang, Jun
;
Wang, Yu-hua
;
Hou, Yuan-yuan
;
Xi, Tao
;
Liu, Yao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
morphine withdrawal
aversive memory
conditioned place aversion
dorsal hippocampus
actin rearrangement
RhoA
Rac1
naloxone
Y27632
NSC23766
thesmallgtpaserhoabutnotrac1isessentialforconditionedaversivememoryformationthroughregulationofactinrearrangementsinratdorsalhippocampus
期刊论文
OAI收割
actapharmacologicasinica, 2013, 卷号: 34, 期号: 6, 页码: 811
作者:
Wang Jun
;
Wang Yuhua
;
Hou Yuanyuan
;
Xi Tao
;
Liu Yao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
TERM SYNAPTIC PLASTICITY
DENDRITIC SPINES
STRUCTURAL PLASTICITY
DRUG-WITHDRAWAL
CYTOSKELETON
DYNAMICS
FAMILY
POLYMERIZATION
MAINTENANCE
EXPRESSION
morphine withdrawal
aversive memory
conditioned place aversion
dorsal hippocampus
actin rearrangement
RhoA
Rac1
naloxone
Y27632
NSC23766
The Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the Phenylephrine-induced Artery Contraction
期刊论文
OAI收割
CURRENT PHARMACEUTICAL DESIGN, 2012, 卷号: 18, 期号: 27, 页码: 4258-4264
作者:
Zhang, Yan
;
Deng, Jing
;
Ma, Sheng
;
Xue, Lin
;
Zhu, Jin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
RhoA/Rho-kinase pathway
HL07
RhoA activation
vasodilation
binding affinities
Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration
期刊论文
OAI收割
ONCOGENE, 2012, 卷号: 31, 期号: 3, 页码: 306-321
Luo, Y
;
Zheng, C
;
Zhang, J
;
Lu, D
;
Zhuang, J
;
Xing, S
;
Feng, J
;
Yang, D
;
YAN, X
;
阎锡蕴
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2013/12/24
cell migration
CD146
ERM proteins
RhoA
RhoGDI1
第一代RhoA小分子抑制剂的发现、及其舒张血管的机制和应用研究
会议论文
OAI收割
作者:
邓菁
;
冯恩光
;
马晟
;
张彦
;
李洪林
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
小分子抑制剂
第一代
舒张血管
RhoA