机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2023 [1]
• 2022 [1]
• 2017 [1]
• 2015 [1]
• 2014 [2]
• 2010 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20 作者:  Shi, Huanyu;  Tang, Haotian;  Li, Yan;  Chen, Danqi;  Liu, Tongchao   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/04/10 Cancer immunotherapy  SAR study  HPK1 inhibitors  Quinazoline-2  5-diamine  IL-2 production   Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12 作者:  Lu, Haibo;  Lu, Tian;  Zu, Shijia;  Duan, Zhe;  Guang, Yiman   |  收藏  |  浏览/下载：46/0  |  提交时间：2022/08/16 CECR2 bromodomain  BPTF bromodomain  Small-molecule inhibitor  SAR study  Chemical probe   Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation 期刊论文  OAI收割 ACS INFECTIOUS DISEASES, 2017, 卷号: 3, 期号: 3, 页码: 199-205 作者:  Lu, Dong;  Liu, Feifei;  Xing, Weiqiang;  Tong, Xiankun;  Wang, Lang   |  收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 pyridazinone  HBV DNA-free capsids  drug-like optimization  SAR study  lead candidate   Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 19, 页码: 6427-6436 作者:     |  收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 FXR  FXR antagonist  SAR study  Non-steroidal   Design, synthesis, and SAR of embelin analogues as the inhibitors of PAI-1 (plasminogen activator inhibitor-1) 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2379-2382 作者:  Chen, Fanglei;  Zhang, Guiping;  Hong, Zebin;  Lin, Zhonghui;  Lei, Min   |  收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 Embelin  Natural product  PAI-1  Inhibitory activity  SAR study   Discovery and SAR study of hydroxyacetophenone derivatives as potent, non-steroidal farnesoid X receptor (FXR) antagonists 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 5, 页码: 1596-1607 作者:  Liu, Peng;  Xu, Xing;  Chen, Lili;  Ma, Lei;  Shen, Xu   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 FXR antagonist  SAR study  Hydroxyacetophenone derivatives  Non-steroidal   Structural modification of a specific antimicrobial lead against Helicobacter pylori discovered from traditional Chinese medicine and a structure-activity relationship study 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 45, 期号: 11, 页码: 5258-5264 作者:  Zhang, Bang-Le;  Fan, Cheng-Qi;  Dong, Lei;  Wang, Fang-Dao;  Yue, Jian-Min   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Anti-Helicobacter pylori lead  Structural modification  SAR study