中国科学院机构知识库网格
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Ent-labdane-type diterpene glycosides obtained from
Rubus
chingii
Hu and their inhibitory effects on PDE5A activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 173, 页码: 14
作者:
Yu, Jun-dong
;
Wang, Jing-Yi
;
Liu, Jia-yuan
;
Xu, Ye-chun
;
Zhang, Xue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
diterpene glycosides
Rubus Chingii Hu
PDE5A inhibitory activity
ent-labdane
Eleven highly oxygenated and anti-inflammatory guaian-8,12-olides from Hedyosmum orientale
期刊论文
OAI收割
TETRAHEDRON, 2024, 卷号: 152, 页码: 8
作者:
Fan, Yao-Yue
;
Zhang, Xin-Ru
;
Zheng, Cheng-Yu
;
Li, Ying
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Hedyosmum orientale
Natural products
Guaian-8,12-olide
Structure elucidation
Anti-inflammatory activity
Structure-Activity Relationships of 2-(Arylthio)benzoic Acid FTO Inhibitors
期刊论文
OAI收割
ISRAEL JOURNAL OF CHEMISTRY, 2024, 页码: 13
作者:
Yan, Chao
;
Zhang, Qian
;
Xiao, Pan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/25
RNA modification
m(6)A
FTO
anticancer
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 2, 页码: 6
作者:
Zhu, Yingli
;
Qian, Jie
;
Yu, Kunqian
;
Hou, Jing
;
Ma, Yeshuo
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
Theranostic probe
Artificial intelligence
Conformational restriction
Fluorescence restoration
Design strategy
Dual-signal viscosity flow paper sensor for ATP detection based on bio-recognition and nanozyme activity regulation of ZIF-90
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2024, 卷号: 481, 页码: 9
作者:
Wang, Yingwen
;
Qi, Peng
;
Zhang, Dun
;
Zeng, Yan
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/04/07
Paper-based ATP assay
Degradation of high viscosity hydrogel
Nanozyme reactivation
Onsite detection
ZIF-90
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
;
Osman, Ezzat E. A.
;
Wang, Xiao-Juan
;
Choo, Yeun-Mun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2
期刊论文
OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:
Liu, Yaowen
;
Nie, Tianqing
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/13
3CLpro
SARS-CoV-2
Betulinic acid
Natural product
Inhibitory activity
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense