机构

• 上海药物研究所 [3]
• 金属研究所 [2]
• 上海神经科学研究所 [2]
• 生物物理研究所 [1]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2013 [2]
• 2010 [3]
• 2006 [3]

学科主题

• Biochemist... [2]
• Neuroscien... [1]

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction   Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu   |  收藏  |  浏览/下载：16/0  |  提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction   Regulation of beta cleavage of amyloid precursor protein 期刊论文  OAI收割 NEUROSCIENCE BULLETIN, 2010, 卷号: 26, 期号: 5, 页码: 417-427 Wang, Jun-Feng; Lu, Rui; Wang, Yi-Zheng 收藏  |  浏览/下载：20/0  |  提交时间：2012/07/13 Alzheimer's disease  amyloid beta peptide  amyloid precursor protein  beta secretase  APP TRANSGENIC MICE  ALZHEIMERS-DISEASE  A-BETA  SECRETASE ACTIVITY  PLAQUE-FORMATION  GAMMA-SECRETASE  GENE-EXPRESSION  IN-VIVO  BACE1  BRAIN   Calpain Activation Promotes BACE1 Expression, Amyloid Precursor Protein Processing, and Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 卷号: 285, 期号: 36, 页码: 27737-27744 作者:  Luo, Zhen-Ge 收藏  |  浏览/下载：26/0  |  提交时间：2012/07/13 BETA-SECRETASE ACTIVITY  IN-VIVO  BRAIN-INJURY  WATER-MAZE  MICE  PRESENILIN-1  NEURODEGENERATION  DEPOSITION  CALCIUM  P25   Predicting memapsin 2 (beta-secretase) hydrolytic activity 期刊论文  OAI收割 PROTEIN SCIENCE, 2010, 卷号: 19, 期号: 11, 页码: 2175-2185 Li, Xiaoman; Bo, Huang; Zhang, Xuejun C; Hartsuck, Jean A; Tang, Jordan 收藏  |  浏览/下载：32/0  |  提交时间：2013/12/24 memapsin 2  BACE1  beta-secretase  subsite specificity  activity prediction  beta-amyloid  Alzheimer's disease   Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relationship to beta-secretase 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 期号: 12, 页码: 1586-1593 作者:  Hu, Bin;  Xiong, Bing;  Qiu, Bei-Ying;  Li, Xin;  Yu, Hai-Ping   |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 beta-secretase  hydroxyethylene  OM99-2  Alzheimer's disease  structure-activity relationship   constructionofasmallpeptidelibraryrelatedtoinhibitorom992anditsstructureactivityrelationshiptobsecretase 期刊论文  OAI收割 actapharmacologicasinica, 2006, 卷号: 27, 期号: 12, 页码: 1586 作者:  Bin Hu;  Bing Xiong;  Beiying Qiu;  Xin Li;  Haiping Yu   |  收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 b-secretase  hydroxyethylene  OM99-2  Alzheimer's disease  structure_activity relationship   Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relationship to b-secretase 期刊论文  OAI收割 Acta Pharmacologica Sinica, 2006, 卷号: 27, 期号: 12, 页码: 1586 作者:  Bin Hu;  Bing Xiong;  Beiying Qiu;  Xin Li;  Haiping Yu   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 b-secretase  hydroxyethylene  OM99-2  Alzheimer's disease  structure_activity relationship