中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
昆明植物研究所 [7]
地理科学与资源研究所 [1]
武汉病毒研究所 [1]
过程工程研究所 [1]
中国科学院大学 [1]
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采集方式
OAI收割 [24]
iSwitch采集 [2]
内容类型
期刊论文 [26]
发表日期
2025 [1]
2024 [2]
2023 [2]
2022 [1]
2021 [1]
2020 [1]
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学科主题
Pharmacolo... [2]
Oncology [1]
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In vitro
and
In vivo
Drug Metabolism Analysis of BPI-460372-A Covalent TEAD1/3/4 Inhibitor
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2025, 页码: 15
作者:
Liu, Xiaoyun
;
Zhong, Dafang
;
Tang, Chongzhuang
;
Xu, Xiaofeng
;
Lan, Hong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/24
Hippo signaling pathway
TEAD inhibitor
covalent inhibitor
BPI-460372
UHPLC-Orbitrap-HRMS
cysteine
S
-conjugate
beta
-lyase.
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Liu, Yadan
;
Ye, Jialin
;
Fan, Zisheng
;
Wu, Xiaolong
;
Zhang, Yinghui
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/12/16
cGAS-STING signaling
Ginkgetin
senescence
STING inhibitor
target identification
Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2024, 页码: 14
作者:
Zhang, Yinghui
;
Liu, Yadan
;
Jiang, Bing
;
Chen, Lifan
;
Hu, Jie
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/10/21
cGAS-STING signaling
STING inhibitor
TransformerCPI model
Licochalcone D
inflammatory diseases
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:
Yang,Qihong
;
Qin,Tong
;
An,Tao
;
Wu,Hongna
;
Xu,Gang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/07/30
PORCN inhibitor
WHN-88
Palmitoylation
Wnt-driven cancers
SIGNALING PATHWAY
PORCUPINE
STEM
GENE
ACYLTRANSFERASE
MUTATIONS
POLARITY
PROTEIN
RNF43
MICE
Small-Molecule Drugs in Immunotherapy
期刊论文
OAI收割
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:
Hao,Xuanrun
;
Chen,Zhongliang
;
Li,Haining
;
Wei,Minqin
;
Zuo,Zhili
  |  
收藏
  |  
浏览/下载:174/0
  |  
提交时间:2024/07/25
Cancer immunotherapy
inhibitors
Pd-1/Pd-L1 inhibitor
IDO inhibitor
STING agonists
ROR gamma t agonists
TGF
beta inhibitors
INDOLEAMINE 2,3-DIOXYGENASE
SIGNALING INHIBITOR
DENDRITIC CELLS
GROWTH
TUMOR
PATHWAY
PEMBROLIZUMAB
RECEPTORS
DISCOVERY
VADIMEZAN
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
Herbivory-induced systemic signals are likely to be evolutionarily conserved in euphyllophytes
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL BOTANY, 2021, 卷号: 72, 期号: 20, 页码: 7274-7284
作者:
Lei,Yunting
;
Xu,Yuxing
;
Zhang,Jingxiong
;
Song,Juan
;
Wu,Jianqiang
  |  
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2022/04/02
Dodder
evolution
herbivory
jasmonic acid
systemic signaling
vascular plants
LONG-DISTANCE
LAND
BIOSYNTHESIS
INHIBITOR
MECHANISM
LEAVES
PLANTS
GENE
H2O2, Ca2+, and K+ in subsidiary cells of maize leaves are involved in regulatory signaling of stomatal movement
期刊论文
OAI收割
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 2020, 卷号: 152, 页码: 243-251
作者:
Zhang, Li
;
Li, Dongyang
;
Yao, Yaqin
;
Zhang, Suiqi
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/03/23
H2O2
Ca2+
K+
Subsidiary cells
Stomatal movement
Signaling substance
Inhibitor
2-ethoxystypandrone, a novel small-molecule stat3 signaling inhibitor from polygonum cuspidatum, inhibits cell growth and induces apoptosis of hcc cells and hcc cancer stem cells
期刊论文
iSwitch采集
Bmc complementary and alternative medicine, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/05/08
Polygonum cuspidatum
2-ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
Stat3 signaling pathway
Cancer stemness inhibitor
2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells
期刊论文
OAI收割
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Polygonum cuspidatum
2-Ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
STAT3 signaling pathway
Cancer stemness inhibitor