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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [238]
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大连化学物理研究所 [42]
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期刊论文 [803]
学位论文 [23]
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Physics [13]
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Solid-state screening and dry powder inhaler development of ziyuglycoside II sodium salt for enhanced bioavailability
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 681, 页码: 11
作者:
Zhang, Hanwen
;
Wang, Siwen
;
Slimani, Sara
;
Lv, Yuting
;
Nie, Qin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Bioavailability
Dry powder inhaler
Saponin
Solid-state screening
Ziyuglycoside II sodium salt
Screening and functional characterization of nanobodies targeting the transferrin receptor
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2025, 卷号: 231, 页码: 7
作者:
Ding, Yuting
;
Jia, Li
;
Geng, Qifubo
;
Liu, Yan
;
Guo, Shaojue
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/05/27
Transferrin receptor (TfR1)
Nanobody screening
Cancer therapy
Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Li, Kun
;
Zeng, Yue
;
Xiong, Yi-da
;
Wu, Hao-chen
;
Fang, Sui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
drug-target affinity prediction
virtual screening
contrastive learning
graph neural network
N
-methyl-
D
-aspartate (NMDA) receptors
GluN3A subunit.
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8
作者:
Wang, Shi-hang
;
Zeng, Yue
;
Yang, Hao
;
Tian, Si-yuan
;
Zhou, Yong-qi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/25
N
-methyl-
D
-aspartate receptors
GluN1/GluN3A
ligand-based virtual screening
scaffold hopping
deep learning
GeminiMol
Screening of botanical drugs reveals the potential anti-human adenovirus activity of berberine
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2025, 卷号: 237, 页码: 9
作者:
Cao, Junyuan
;
Zhang, Hao
;
Zhang, Jixiang
;
Wang, Jinlin
;
Li, Chen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/04/24
Human adenovirus
Antiviral drug
Berberine
High-throughput screening
High-affinity nanobodies targeting IL-12B for the detection of fluorescence resonance energy transfer
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2025, 卷号: 229, 页码: 9
作者:
Hu, Jing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/04/24
Nanobody screening
IL-12B
Phage display technology
Fluorescence resonance energy transfer
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Deciphering the key drivers of oxidative potential during ammonium nitrate-mediated aqueous-phase photoreaction of methoxyphenols
期刊论文
OAI收割
ATMOSPHERIC ENVIRONMENT, 2025, 卷号: 340, 页码: 10
作者:
Lai, Racliffe Weng Seng
;
Qiu, Tian
;
Zhang, Xuyang
;
Wang, Yalin
;
Hao, Tianwei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Biomass burning
Methoxyphenol
Aqueous secondary organic aerosol
DTT consumption
Non-target screening analysis
Profiling metabolites and exploring metabolism of parabens in human urine using non-target screening and molecular networking
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2024, 卷号: 480, 页码: 10
作者:
Yang, Tao
;
Li, Xinling
;
Tan, Jianhua
;
Liang, Wenyao
;
Kuang, Hongxuan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/01
Parabens
Non-target screening
Molecular network
Metabolic pathway
Human urine