中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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A Hybrid-Targeting Nanoparticle for Penetrable Delivery of Temozolomide to Enhance Glioblastoma Therapy
期刊论文
OAI收割
NANO LETTERS, 2025, 卷号: 25, 期号: 19, 页码: 7989-7997
作者:
Wang, Guanru
;
Guo, Hao
;
Wei, Mengxin
;
Wang, Ying
;
Jin, Zengcai
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
glioblastoma
chemotherapy
drug delivery
tumor-specific drugaccumulation
tumor-suppressiveeffects
De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Direct Preparation of Site-Specific Antibody-Drug Conjugates with Unpurified Antibodies in Culture Medium
期刊论文
OAI收割
CHEMBIOCHEM, 2025, 页码: 7
作者:
Lu, Mengru
;
Zeng, Yue
;
Hang, Jiaying
;
Shi, Wei
;
Huang, Wei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
cellular expression systems
K248 site-specific ADCs
one-pot
Species-Specific Responses of Fine Root Morphology, Anatomy, and Mycorrhizal Traits to Nitrogen Addition in Temperate Forest Ecosystems
期刊论文
OAI收割
ENVIRONMENTAL ENGINEERING SCIENCE, 2025, 卷号: N/A
作者:
Zhou, Mingxin
;
Li, Yibo
;
Hao, Jiantao
;
Ying, Pengcheng
;
Yang, Tianlun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/03/18
climate change
ecosystem management
fine root plasticity
mycorrhizal traits
nitrogen addition
species-specific responses
Thermodynamics performance assessment of precooled cycle engines with ammonia as the fuel and coolant
期刊论文
OAI收割
ACTA MECHANICA SINICA, 2025, 卷号: 41, 期号: 2, 页码: 18
作者:
Zhang X(张鑫)
;
Lu Y(陆阳)
;
Fan XJ(范学军)
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/10/21
Ammonia
PC-RT
PC-GT
Specific thrust
Specific impulse
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Behavioral and electrophysiological evidence for preserved specific associative episodic memory in older adults
期刊论文
OAI收割
NEUROPSYCHOLOGIA, 2024, 卷号: 204, 页码: 11
作者:
Miao, Jingwen
;
Liu, Xiaomei
;
Zheng, Zhiwei
;
Weigl, Michael
;
Cui, Xiaoyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/11/26
Older adults
Specific memory
Context reinstatement
Event-related potentials
Involuntary recollection
GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states
期刊论文
OAI收割
BMC BIOINFORMATICS, 2024, 卷号: 25, 期号: 1, 页码: 16
作者:
Liu, Fan
;
Zhou, Han
;
Li, Xiaonong
;
Zhou, Liangliang
;
Yu, Chungong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/06
G-protein coupled receptor
State-specific structure
Binding site
Key residue
Database
Measurement While Drilling Method for Estimating the Uniaxial Compressive Strength of Rocks Considering Frictional Dissipation Energy
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF GEOMECHANICS, 2024, 卷号: 24, 期号: 11, 页码: 14
作者:
Cheng, Xu
;
Tang, Hua
;
Wu, Zhenjun
;
Qin, Hui
;
Zhang, Yonghui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/27
Measurement while drilling
Specific energy
Uniaxial compressive strength
Granite
Sandstone
Limestone
Soil heavy metal pollution promotes extracellular enzyme production by mediating microbial community structure during vegetation restoration of metallic tailing reservoir
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 948, 页码: 11
作者:
Zhao, Dongyan
;
Bol, Roland
;
Wang, Jipeng
;
Jin, Jiyuan
;
Wang, Yuhan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/08/27
Specific enzyme activity
Microbial community structure
Heavy metal pollution
Soil nutrients
Ecological restoration chronosequence